Treponema Pallidum

causes syphilis. Human only host and reservoir. STD.

STD. gay and bisexual men, prostitues and IV drug.

Direct contact with mucous membrane . Spirochete bind to epithelium using its hooked tip. and forms a CHANCRE. Chancre fluids highly contagious . Lesion heals as the spriochetes moves into the blood.

spirochete in blood. Red or brown rash forms on the skin, palms, and soles w/fever headache and sore throat. Lesions contain viable spirochetes. Rash disappears spontaneously.

Inter latent period that can last 20 years. if untreated tertiary syphillis will form. Damage multiple tissues and organs; neurosyphillis . GUMMAS are lesions that develop in the bone, nervous tissue, liver or skin

can pass through placenta to the fetus inhibiting fetal growth and development. Nasal discharge, skin eruption, bone deformation and N.S. abnormallities. Incisions in mouth

Microscopy, fluorescent, penicillin