Nutrition Chapter 13

25 July 2022
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most B-vitamins function as
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coenzymes
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in which of the following metabolic pathways are coenzymes required?
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glycolysis; citric acid cycle; beta-oxidation; electron transport chain
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in general, excess amounts of water-soluble vitamins are excreted via
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kidneys
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nutritionally, the difference between brown rice and white rice is
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the presence of bran and germ layers in the brown rice, which have most of the nutrients
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the nutrients added to enriched grains typically include
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thiamin, riboflavin, niacin, folic acid, and iron
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the vitamin that prevents beriberi is
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thiamin
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thiamin pyrophosphate (TPP), the coenzyme form of thiamin, is
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essential or the oxidative decarboxylation of pyruvate
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thiamin should be given to an alcoholic patient who has
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Wernicke-Korsakoff syndrome
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a nutrient-dense source of thiamin is
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pork and pork products
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the best sources of thiamin in the average diet are
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pork products, whole or enriched grains and cereals, and legumes
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a deficiency of thiamin that affects the cardiovascular, muscular, nervous, and gastrointestinal systems is called
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beriberi
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the coenzyme form of riboflavin is
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FAD
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riboflavin coenzymes function in a variety of metabolic pathways, such as
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beta-oxidation of fatty acids; the citric acid cycle; the electron transport chain
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which of the following foods represents the most nutrient-dense source of riboflavin?
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low-fat milk
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the B-vitamin most easily destroyed by exposure to light is
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riboflavin
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a painful, red, inflamed tongue is called
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glossitis
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in the average U.S. diet, a quarter of the riboflavin comes from one food group, the
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milk group
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to protect riboflavin from destruction by sunlight, milk and milk products are packaged in
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paper and opaque plastic cartons
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one cause of fatigue and anemia in adolescent girls with low dairy intake is deficiency of
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riboflavin
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the riboflavin coenzymes have __________ functions in cellular metabolism
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oxidation and reduction
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an excess intake of riboflavin either from diet or supplements is mainly
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excreted in the urine
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niacin can be obtained from foods as the vitamin itself (preformed niacin) or be synthesized
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from the essential amino acid tryptophan
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a characteristic symptom of niacin deficiency is
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inflammation of the skin after exposure to the sun
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the coenzyme forms of niacin include
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NAD and NADP
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niacin is necessary in the diet to prevent the disease called
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pellagra
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the fact that the amino acid tryptophan can be converted to niacin by the body explains why
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digests high in protein could prevent or cure pellagra
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bright yellow urine usually is indicative that someone is supplementing with
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riboflavin
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flushing got the face and skin can result from pharmacological doses o
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niacin
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the nutrient sometimes prescribed by physicians to increase HDL-cholesterol and lower triglyceride levels is
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niacin
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important contributors to niacin intake in the American diet are
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poultry, meat, and fish
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thiamin, niacin, and riboflavin work together in important biochemical pathways that
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release energy from carbohydrate, fat, and protein
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a diet that provides 75g protein per day can contribute ________________ mg niacin from tryptophan
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12.5
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the niacin coenzyme is reduced (NAD+ -> NADH + H+) during
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glycolysis; the pyruvate decarboxylation reaction; the citric acid cycle
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which of the foods listed below his the lowest niacin bioavailability?
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corn
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an essential component of coenzyme A is
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pantothenic acid
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pantothenic acid is a part of __________, an important biochemical compound
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acetyl-CoA
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which of the following B-vitamins is found in the widest variety of foods (I.e.., different food groups such as vegetables, grains, meat)?
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pantothenic acid
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biotin is needed for
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gluconeogenesis
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biochemical reactions that add CO2 to counts often requires
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biotin
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the protein in raw egg whites that can bind biotin is called
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avidin
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a high intake o raw egg whites (>12 per day) can inhibit absorption of
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biotin
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those most likely to experience a biotin deficiency are
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infants lacking an enzyme required for biotin absorption
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pyridoxal, pyridoxine, and pyridoxal ins are three or suha0114@aol.com of
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vitamin B-6
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pyridoxal phosphate
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participates in reactions that synthesize dispensable amino acids
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neurotransmitter synthesis requires the vitamin B-6 coenzyme. Which of the following is classified as a neurotransmitter?
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norepinephrine; gamma-aminobutyric acid (GABA)
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the best food sources of vitamin B-6 are
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meats. fish, and poultry
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symptoms of vitamin B-6 deficiency include
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depression, confusion, and convulsions; micro cystic anemia; dermatitis
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irreversible nerve damage may be caused by excessive intake of __________ supplements
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vitamin B-6
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in edition to its role in amino acid metabolism, vitamin B6 is also required for
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the release of glucose from glycogen
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research shows that supplemental vitamin B-6 is most likely to aid those experiencing
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nausea associated with pregnancy
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red blood cells turn over every
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120 days
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to calculate the DFE for the diet, multiply total synthetic folic acid intake by __________; add that to the total food folate
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1.7
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in a dietary deficiency of folate, there are decreasing numbers of mature red blood cells to carry the oxygen from the lungs to the tissues. this condition is known as
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megaloblastic anemia
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a biochemical function of THFA (tetrahydrofolate) is
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accepting or donating single-carbon molecules in various metabolic pathways
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a major role of folate in cellular metabolism is the
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synthesis of purine and pyrimidine bases in RNA and DNA
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the cells most sensitive to a deficiency of dietary folate are cells that
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have a short life span and rapid turnover rate
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__________ are very large immature red blood cells, which are formed as a result of folate
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megaloblasts
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a defect in the formation of the neural tube during early fetal development can occur from a lack of
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folate
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about 50% to 90% of folate in foods can be destroyed by
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food processing and preparation; ultraviolet light; oxidation
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good sources of folate include
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enriched cereals and grains; leafy green vegetables; oranges; dried beans
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the form of folate that is best absorbed is the
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monoglutamate form found in supplements and fortified foods
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it's very difficult to consume excess folic acid from nonprescription vitamin supplements
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the FDA limits the amount of folic acid in supplements to 400 micrograms per capsule
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which group of individuals has the highest requirement for folate?
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pregnant women
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which group of individuals is advised to consume 400 micrograms of folic acid daily from supplements and/or fortified foods?
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women capable of becoming pregnant
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vitamin B-12 is supplied mostly in
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foods of animal origin
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persons who smoke have an increased need for
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vitamin C
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intrinsic factor is produced by the
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parietal cells of the stomach
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vitamin B-12 is absorbed in the
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ileum
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for vitamin B-12 to be absorbed, it must be attached to
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intrinsic factor
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the B-vitamin that has significant liver stores is
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vitamin B-12
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individuals most likely to experience poor vitamin B-12 status are
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elderly adults, due to strophic gastritis
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pernicious anemia is treated most often by
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regular intramuscular injection of vitamin B-12
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a major role of vitamin B-12 in cellular metabolism is
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transfer of a methyl group to the amino acid homocysteine, forming the amino acid methionine
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megaloblastic anemia develops as a result of deficiencies of __________ and __________
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folate; vitamin B-12
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which of the following actors can interfere with the absorption of vitamin B-12?
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surgical removal of the stomach; defective R-protein synthesis; infections of the ileum or surgical removal of the ileum
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a strict vegan diet may lack
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vitamin B-12
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vitamin B-12 is found in which of the following foods?
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chicken
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supplements of the water-soluble vitamins __________ and __________ are most likely to cause toxicity symptoms
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vitamin B-6; vitamin C
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formation and maintenance of collagen requires
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vitamin C
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ingestion of vitamin C meals can modestly improve absorption of
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nonheme iron
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the primary function of vitamin C in cellular metabolism is to
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act as nonspecific reducing agent (electron donor)
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which meal contains the highest amount of vitamin C?
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baked fish with lemon, broccoli cole slaw, and strawberries
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the first symptom of scurvy is
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pinpoint hemorrhages around hair follicles
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physiological changes associated with scurvy (hemorrhages, joint pain, fractures) are caused by
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defective collagen synthesis
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which group of foods provides substantial amounts of vitamin C?
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citrus fruits and vegetable
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factors such as heat, iron, copper, and oxygen
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destroy vitamin C in foods
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scurvy is due to a deficiency of
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vitamin C
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the RDA for vitamin C is increased by __________mg/day for smokers
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35
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the amino acids __________ and __________ are hydroxylated with the aid of vitamin C to form strong connective tissue
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proline; lysine
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at intakes of supplemental vitamin C greater than 2 g/day, adverse effects, including __________, may occur
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gastrointestinal bloating and diarrhea
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choline is required for the synthesis of
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phospholipids and lipoproteins
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rich sources of choline are
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meats, eggs, and dairy products
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the compound carnitine is required for
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transport of fatty acids into mitochondria