BME

25 July 2022
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53 test answers

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question
What causes pernicious anemia?
answer
A vitamin deficiency
question
In 1889, Oscar Minkowski removed an organ from a dog. The dog subsequently developed symptoms similar to diabetes patients. What was the organ?
answer
Pancreas
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An IACUC (Institutional Animal Care and Use Committee) weighs the scientific benefit of the application versus:
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The harm caused to the animals
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Choose the two main functions of the pancreas: (Select 2 of the 4 answers)
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It produces and secretes digestive enzymes into the stomach It controls glucose level in the blood stream through the secretion of insulin
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Fred Banting grew up:
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On a farm.
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Currently, if a scientist wants to experiment on mammals, the scientist's experiment must be approved by a committee that is composed entirely of other scientists.
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False
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Fred Banting entered medical school:
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After dropping out of college
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Classic symptoms of diabetes include:
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Excessive urination
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Blood test are only for measuring the number of red blood cells a person has.
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False
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Around 1920, the amount of glucose in blood could be measured by an electronic meter.
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False
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Charles Evan Hughes, the US Secretary of State in 1920, was diagnosed with diabetes in 1920.
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False
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During the summer of 1921, Fred Banting performed experiments on dogs. In one group of dogs, he tried to cause the dogs to develop diabetes by removing an organ. Which organ did he remove:
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Pancreas
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Fred Banting developed his idea on how to treat diabetes while he was:
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preparing a lecture for medical students
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In 1921, the best way to measure glucose in blood was based on:
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the final color of a mixture of blood and some reagents
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A child who develops diabetes typically loses weight. In 1920, the best treatment for this child would be to:
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restrict diet, causing more weight loss
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The best treatment for diabetes about 1915 was known as:
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starvation diet
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In 1920 the company Eli Lilly was known for manufacturing
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Capsules for drugs
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Arnold Beckman invented and sold one of the first integrated
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pH meters
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James Collip, at the University of Toronto, developed a method to isolate insulin based upon
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The solubility of insulin in alcohol/water mixtures
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James Collip needed an assay for the activity of insulin in order to develop a purification method. His assay for insulin activity was based upon:
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Measuring the change in blood sugar levels in rabbits
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George Walden was the engineer at the Eli Lilly in charge of insulin production and purification. George Walden's major contribution was that:
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He invented isoelectric precipitation.
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The quantity known as pH measures:
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The concentration of hydrogen ions in a solution
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The University of Toronto licensed a patent on the production of insulin to Eli Lilly. The agreement allowed Eli Lilly to manufacture and sell insulin. In return, Eli Lilly would give the University of Toronto
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5% of Eli Lilly's net sales from the insulin
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Fred Banting died in 1941 from:
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Plane crash
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Professor Dorothy Hodgkin was awarded the Nobel Prize in 1964 for deciphering the structure of insulin using the technique of X-ray crystallography.
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False
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The order of amino acids in a protein produced by your body is
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determined by your DNA
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X-ray crystallography can be used to
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determine the three dimensional structure of a protien.
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This technique reveals the structure of complex molecules:
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X-ray crystallography
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Molecular dynamics simulations show that the structure of proteins
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is dynamic; proteins constantly shake and bend.
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The birth control drug Nexplanon is usually implanted under the skin of a woman's:
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Arm
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The Ames Reflective Meter was one of the first:
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Home based blood glucose meters
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Glucose Oxidase was isolated from:
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fungus
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Dick Bernstein was one of the first people to :
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Have a home blood glucose meter
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The Diabetes Control and Complications Trial tested whether this method of treating diabetes was better than what patients had been doing:
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Tight control of glucose levels
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One conclusion from the Diabetes Control and Complications Trial was that tight control:
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Minimized long term complications
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A complete lack of vitamin A in a person's diet can lead to:
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Blindness
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The loose control approach to managing a patient's diabetes can be characterized by the following:
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freedom to eat whatever they choose and a single dose of insulin per day
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Patients enrolled in the Diabetes Control and Complications Trial were randomly assigned to be part of the tight control group or the standard group.
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True
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An insulin molecule in circulating in your bloodstream consists of:
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two chains of amino acids linked together by disulfide bonds
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From the 1920s through the 1960s, insulin used by patients with diabetes came from which sources:
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pigs and cows
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Engineered E. coli bacteria containing recombinant DNA is not dangerous to humans because:
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it is incapable of surviving outside well controlled laboratory environments.
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In the 1960's, the annual supply of insulin was limited by:
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the number of cows and pigs slaughtered each year
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Today, most insulin in produced in a large factory by which types of organisms:
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yeast or bacteria
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A closed loop system for insulin delivery contains:
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an insulin pump and a continuous blood glucose meter.
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An insulin pen differs from an insulin pump because
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an insulin pump is attached to your body by tubing, but an insulin pen is not.
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The label of a prescription drug:
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summarizes all the scientific information known about the drug.
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Afrezza and Exubera are two different insulin delivery systems. The most notable difference between the two is:
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the inhaler for Exubera is much larger than the inhaler for Afrezza.
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Off label prescribing is when
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a physician prescribes a drug to treat a condition that was NOT approved by the FDA.
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In the 1960's Margaret Crane was working as a :
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product packaging designer
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The HbA1c test measures how much of this molecule is attached to hemoglobin.
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glucose
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The self-orienting millimeter scale applicator (SOMA) is a device that might allow oral delivery of insulin, or an insulin pill. The shape of the SOMA is based on the shape of which animal:
answer
turtle
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Diabetes (type 1) is caused by
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autoimmune reaction
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The HbA1c test is named after:
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A line of hemoglobin observed on a gel.