Which of the following substances is not normally found in filtrate?
-ions, such as sodium and potassium
-blood cells and large particles
-nitrogenous waste particles, such as urea
-water and small solutes
answer
blood cells and large particles
question
What is the primary driving force (pressure) that produces glomerular filtration?
-hydrostatic pressure of blood (blood pressure)
-colloid osmotic pressure of blood
-gravity
answer
hydrostatic pressure of blood (blood pressure)
question
Which substance would be found in higher concentration if the membrane were damaged?
-creatinine
-glucose
-chloride
-protein
answer
protein
question
If the osmotic pressure in the glomerular capillaries increased from 28 mm Hg to 35 mm Hg, would net filtration increase or decrease?
-net filtration would not be altered
-net filtration would decrease
-net filtration would increase
answer
net filtration would decrease
question
Which of the following statements about aldosterone is NOT correct?
-Aldosterone is produced in the adrenal cortex.
-Aldosterone increases the number of passive sodium channels in the luminal membrane of the distal tubule and collecting duct, thus aiding sodium reabsorption.
-Aldosterone is stimulated by decreased plasma sodium levels and increased plasma potassium levels.
-Aldosterone increases sodium reabsorption by increasing the number of Na+-K+ ATPase pumps in the luminal membrane of the proximal tubule.
answer
Aldosterone increases sodium reabsorption by increasing the number of Na+-K+ ATPase pumps in the luminal membrane of the proximal tubule.
question
Which of the following statements about ADH (antidiuretic hormone) is correct?
-ADH is released by the posterior pituitary gland.
-ADH would increase urine volume.
-ADH inserts water channels into the luminal membrane of the proximal tubules.
-ADH is synthesized by the adrenal gland and works in the kidney.
answer
ADH is released by the posterior pituitary gland.
question
What is the osmolarity of the filtrate at the end of the proximal tubule?
-hypotonic - 100 mOsm
-hypertonic - 600 mOsm
-hypertonic - 1200 mOsm
-isotonic - 300 mOsm
answer
isotonic - 300 mOsm
question
In overhydration, what would be the levels of ADH (high, normal, or low) and what would be the osmolarity of the urine?
ADH - low; 600 mOsm (urine)
ADH - high; 100 mOsm (urine)
ADH - low; 100 mOsm (urine)
ADH - high; 600 mOsm (urine)
answer
ADH - low; 100 mOsm (urine)
question
In severe dehydration or blood loss, what would be the levels of ADH and what would be the urine flow rate?
-ADH - low; low urine flow rate (0.25 ml/min)
-ADH - high; high urine flow rate (16 ml/min)
-ADH - high; low urine flow rate (0.25 ml/min)
-ADH - low; high urine flow rate (16 ml/min)
answer
ADH - high; low urine flow rate (0.25 ml/min)
question
Which of the following statements about filtrate is INCORRECT?
-The filtrate is similar to blood plasma.
-The filtrate is collected within the renal cortex.
-The filtrate has the same osmotic pressure as blood plasma.
-The filtrate is produced within the proximal convoluted tubule.
answer
The filtrate is produced within the proximal convoluted tubule.
question
How is the proximal convoluted tubule different from the distal convoluted tubule?
-The proximal convoluted tubule is parallel to the vasa recta, just like the distal convoluted tubule.
-The proximal convoluted tubule has numerous aldosterone-regulated solute transport mechanisms, just like the distal convoluted tubule.
-Water reabsorption is always obligatory in the proximal convoluted tubule but not in the distal convoluted tubule.
-The proximal convoluted tubule empties directly into the collecting duct, just like the distal convoluted tubule.
answer
Water reabsorption is always obligatory in the proximal convoluted tubule but not in the distal convoluted tubule.
question
Imagine a situation in which the number of urea leak channels increased dramatically in the ascending limb of the loop of Henle. What could be one likely consequence of this situation?
-Aldosterone-regulated Na+ pump activity would increase dramatically to stabilize the osmotic concentration gradient.
-The increased solute concentration in the vasa recta would stimulate additional water reabsorption.
-The concentration gradient of the renal medulla would remain unaffected.
-The final urine output would increase greatly because of the increase in ADH-regulated water reabsorption.
answer
The increased solute concentration in the vasa recta would stimulate additional water reabsorption.
question
The mechanisms that establish the medullary osmotic gradient depend mostly on the properties of the __________.
-collecting duct
-distal convoluted tubule
-loop of Henle
-glomerular filtration membrane
answer
loop of Henle
question
An increase in the permeability of the cells of the collecting tubule to water is due to a(n) __________.
-increase in the production of aldosterone
-decrease in the production of ADH
-increase in the production of ADH
-decrease in the concentration of blood plasma
answer
increase in the production of ADH
question
The descending limb of the loop of Henle __________.
-is not permeable to water
-contains fluid that becomes more concentrated as it -moves down into the medulla
-is freely permeable to sodium
-none of the above
answer
contains fluid that becomes more concentrated as it moves down into the medulla
question
The main force pushing water and solutes out of the blood across the filtration membrane is __________.
-glomerular blood pressure
-the size of the podocytes
-the thickness of the capillary endothelium
-none of the above
answer
glomerular blood pressure
question
The mechanism of water reabsorption by the renal tubules is __________.
-osmosis
-active transport
-cotransport with sodium ions
-none of the above
answer
osmosis
question
Which of the following three physiological processes are carried out by the nephrons? (Mark ALL that apply.)
Secretion
Filtration
Reabsorption
Digestion
Agglutination
answer
Secretion, Filtration, Reabsorption
question
A ____________ can be done to analyze the chemical and physical properties of urine.
-Lithotripsy
-Urinalysis
-Pyelogram
-Ultrasound
-Complete blood count
-Renal biopsy
answer
Urinalysis
question
The chemical composition of the urine fluctuates throughout the day depending on metabolic activity, water consumption, and urinary output.
The chemical composition of the urine fluctuates throughout the day depending on metabolic activity, water consumption, and urinary output.
True
False
answer
True
question
An important aspect of urine is its density or specific gravity, which is .
1.003-1.030
1.000-1.015
1.041-1.073
1.030-1.040
answer
1.003-1.030
question
All of the following are normal constituents of urine EXCEPT .
-uric acid
-blood
-creatinine
-urea
answer
blood
question
The normal pH range of urine is .
4.5-8
7-9
1-4.5
3.5-7
answer
4.5-8
question
Which of the following is NOT a normal constituent of urine?
Glucose
Creatinine
Sodium
Water
Urea
answer
Glucose
question
The specific gravity of urine is slightly greater than the specific gravity of distilled water.
True
False
answer
True
question
Dehydration would likely ____________ the specific gravity of urine.
Not affect
Increase
Decrease
answer
Increase
question
Michael has been on a high-protein diet for the past few weeks. What effect might this have on the pH of Michael's urine?
Decrease the pH (more acidic)
Increase the pH (more alkaline)
No effect on the pH
answer
Decrease the pH (more acidic)
question
Which of the following might cause a urine sample to appear turbid? (Mark ALL that apply.)
Water
Mucus
Microbes
Crystals
Blood cells
answer
Mucus
Microbes
Crystals
Blood cells
question
All of the following may cause ketones to be found in the urine EXCEPT .
starvation
a diet very low in carbohydrates
a diet very low in protein
diabetes mellitus
answer
a diet very low in protein
question
All of the following may increase the permeability of the glomerular membrane EXCEPT .
disease
low blood pressure
physical injury
bacterial toxins
answer
low blood pressure
question
All of the following may cause urobilinogenuria EXCEPT .
infectious hepatitis
cirrhosis
congestive heart failure
kidney stones
answer
kidney stones
question
What does ketosis, or ketones in the urine, indicate?
Excessive hemoglobin breakdown
Excessive salt consumption in the diet
A urinary tract infection
Excessive lipid catabolism
Increased glomerular permeability
answer
Excessive lipid catabolism
question
A diabetic patient who is poorly regulating the disease would likely have which of the following urine abnormalities? (Mark ALL that apply.)
Ketosis
Urobilinogenuria
Hematuria
Pyuria
Glucosuria
answer
Ketosis
Glucosuria
question
A patient who is suffering from a urinary tract infection (UTI) may have which of the following urine abnormalities? (Mark ALL that apply.)
Nitraturia
Albuminuria
Elevated specific gravity
Pyuria
Bacteriuria
answer
Nitraturia
Albuminuria
Elevated specific gravity
Pyuria
Bacteriuria
question
Which of the following is ABNORMAL urine constituent?
Uric acid
Urea
Creatinine phosphate
Ammonium ions
White blood cells
Chloride ions
answer
White blood cells
question
Presence of bacteria in the urine always indicates a urinary tract infection (UTI) because urine should be free of bacteria.
True
False
answer
False
question
Calculi can become lodged in the kidney, ureters, urinary bladder, or the urethra.
True
False
answer
True
question
The nonsurgical procedure that is performed to break down renal calculi is called _____________.
Urinalysis
Lithotripsy
Hysteroscopy
Pyelogram
Catheterization
answer
Lithotripsy
question
Sediments in the urine consisting of clumps of blood cells, epithelial cells, and crystals are called ___________.
Ketones
Stones
Trichomonas
Casts
Calculi
answer
Casts
question
adventitia
answer
Which structure is highlighted?
adventitia
transitional epithelium
lamina propria
muscular layer
question
arcuate artery
answer
Which structure is highlighted?
arcuate artery
interlobar vein
interlobar artery
arcuate vein
question
arcuate vein
answer
A vessel carrying blood away from the kidney. This vessel is formed by the union of interlobular veins.
Which structure is highlighted?
interlobar artery
arcuate artery
interlobar vein
arcuate vein
question
circular smooth muscle fibers
answer
Which structure is highlighted?
collagen fibers
longitudinal smooth muscle fibers
circular smooth muscle fibers
dense regular connective tissue
question
water conservation
answer
The highlighted structure ( collecting duct) is primarily involved with ________.
maintaining glucose levels
water conservation
regulating ion concentration
urea excretion
question
collecting duct
answer
Which structure is highlighted?
collecting duct
papillary duct
loop of Henle
distal convoluted tubule
question
distal convoluted tubules
answer
Which structures are highlighted?
collecting ducts
proximal convoluted tubules
distal convoluted tubules
glomeruli
question
glomerulus
answer
Which structure is highlighted?
renal corpuscle
juxtaglomerular apparatus
pancreatic islet
glomerulus
question
interlobar artery
answer
Which structure is highlighted?
arcuate artery
interlobar vein
interlobar artery
arcuate vein
question
lamina propria
answer
Which structure is highlighted?
umbrella cells
lamina propria
basement membrane
papillary layer
question
mucosa
answer
To which layer of the ureter wall does the highlighted region belong?
submucosa
muscular layer
adventitia
mucosa
question
inner and outer layers of the detrusor muscle
answer
Which layer or layers of the bladder wall are formed by the highlighted fibers (Longitudinalsmooth muscle fibers)?
The highlighted fibers are randomly distributed throughout the detrusor muscle.
middle layer of the detrusor muscle
inner layer only of the detrusor muscle
inner and outer layers of the detrusor muscle
question
longitudinal smooth muscle fibers
answer
Which structure is highlighted?
circular smooth muscle fibers
longitudinal smooth muscle fibers
dense regular connective tissue
lamina propria
question
loops of Henle
answer
Which structures are highlighted?
peritubular capillaries
collecting ducts
loops of Henle
distal tubules
question
medullary rays
answer
Which structure is highlighted?
medullary rays
renal corpuscles
renal medulla
renal columns
question
muscular layer
answer
Which structure is highlighted?
lamina propria
muscular layer
transitional epithelium
adventitia
question
proximal convoluted tubule
answer
Which structure is highlighted?
renal corpuscle
distal convoluted tubule
glomerulus
proximal convoluted tubule
question
renal corpuscles
answer
Which structure is highlighted?
distal convoluted tubules
glomeruli
proximal convoluted tubules
renal corpuscles
question
filtration
answer
Which process or processes of urine formation occur in the highlighted structure(Glomerulus)?
diffusion
filtration and diffusion
filtration
secretion and re-absorption
question
renal medulla
answer
Which region of the kidney is highlighted?
renal capsule
renal cortex
renal pelvis
renal medulla
question
Urine passes through the __________.
renal pelvis to the ureter to the bladder to the urethra
glomerulus to ureter to renal tubule
hilum to urethra to bladder
renal hilum to the bladder to the ureter
answer
renal pelvis to the ureter to the bladder to the urethra
question
Which is NOT associated with the renal corpuscle?
a vasa recta
a podocyte
a fenestrated capillary
an afferent arteriole
answer
a vasa recta
question
The urinary bladder is composed of __________ epithelium?
pseudostratified columnar
stratified squamous
transitional
simple squamous
answer
transitional
question
The _______ artery lies on the boundary between the cortex and the medulla of the kidney.
interlobar
cortical radiate
arcuate
lobar
answer
arcuate
question
Which of the following statements is correct regarding the ureters?
Ureters have sphincters at their entrances to prevent backflow of urine.
The ureters are lined with stratified squamous epithelium like the skin.
The ureters are capable of peristalsis.
none of the above
answer
The ureters are capable of peristalsis
question
Where are the kidneys located?
Abdominal cavity
Dorsal cavity
Thoracic cavity
Cranial cavity
answer
Abdominal cavity
question
Where is urine stored?
Ureter
Urethra
Urinary bladder
Kidney
Urethra
answer
Urinary bladder
question
What anchors the kidney to the abdominal wall?
Select all that apply.
fibrous capsule
renal fascia
the peritoneal cavity
perinephric fat capsule
answer
renal fascia, perinephric fat capsule
question
The kidneys are located outside the peritoneal cavity.
True
False
answer
True
question
The renal pyramids are located within the renal ______________.
Cortex
Fascia
Medulla
Pelvis
Capsule
answer
Medulla
question
The __________________ merge to form the renal pelvis, which conducts urine into the ureter.
Minor calyces
Renal columns
Renal papillae
Renal hilus
Major calyces
answer
Major calyces
question
Blood vessels, nerves, and the ureter enter the kidney at the renal _____________.
Medulla
Hilus
Pelvis
Columns
Cortex
answer
Hilus
question
Which cells of the kidney monitor NaCl concentrations?
juxtaglomerular cells
macula densa
podocytes
mesangial cells
answer
macula densa
question
The functional and structural unit of the kidneys is the .
nephron
glomerular capsule
loop of Henle
none of the above
answer
nephron
question
The renal corpuscle is made up of .
the descending loop of Henle
the glomerular capsule
the glomerulus and Bowman's capsule
the renal papillae
answer
the glomerulus and Bowman's capsule
question
The majority of the nephrons (approximately 85%) are ______________ nephrons, located primarily in the ______________.
Juxtamedullary; medulla
Cortical; medulla
Cortical; cortex
Juxtamedullary; cortex
answer
Cortical; cortex
question
The renal artery branches into .
interlobar arteries
cortical radiate arteries
arcuate arteries
segmental arteries
answer
segmental arteries
question
What drains the blood from the glomerulus?
efferent arteriole
afferent arteriole
renal artery
arcuate arteries
answer
efferent arteriole
question
Blood from the abdominal aorta enters the kidney via the _____________.
Interlobar vein
Renal artery
Renal vein
Peritubular capillaries
Arcuate artery
answer
Renal artery
question
What type of epithelium line the urethral mucosa?
stratified cuboidal epithelium
stratified squamous epithelium
transitional epithelium
none of the above
answer
stratified squamous epithelium
question
The ureters and the urethra join the urinary bladder on the _________________ surface.
Superior and anterior
Inferior and anterior
Superior and posterior
Inferior and posterior
answer
Inferior and posterior
question
The renal ____________ is an expanded extension of the ____________.
Papilla; urethra
Pelvis; ureter
Papilla; ureter
Pelvis; urethra
answer
Pelvis; ureter
question
Which of the following blood vessels conducts oxygenated blood into the kidney from the abdominal aorta?
Segmental artery
Interlobar artery
Renal vein
Renal artery
Interlobar vein
answer
Renal artery
question
The human kidney and the sheep kidney are very similar in both size and structural anatomy.
True
False
answer
True
question
Cortex
answer
Which structure is highlighted?
minor calyx
medulla
major calyx
cortex
question
interlobar
answer
Which vein is highlighted?
interlobar
corticoradiate
arcuate
renal
question
kidneys
answer
Which organ(s) is/are highlighted?
kidneys
urinary bladder
spleen
adrenal glands
question
removal of toxins from the blood
answer
What is a function of the highlighted organ?
production of new red blood cells
production of parathyroid hormone
removal of toxins from the blood
recycling of red blood cells
question
membranous urethra
answer
Which structure is highlighted?
ureter
prostatic urethra
spongy urethra
membranous urethra
question
transport of urine
answer
What is the primary function of the highlighted structures (Minor calices)?
reabsorption of water
transport of urine
secretion
filtration of the blood
question
renal pelvis
answer
Which structure is highlighted?
renal vein
major calyx
renal pelvis
ureter
question
urinary bladder
answer
Which structure is highlighted?
ureter
kidney
urinary bladder
prostate
question
transitional
answer
What type of epithelium lines the highlighted structure?
transitional
simple squamous
pseudostratified columnar
stratified squamous
question
arcuate
answer
Which blood vessels are highlighted?
afferent
interlobar
arcuate
cortical radiate
question
collecting duct
answer
Which structure is highlighted?
renal corpuscle
collecting duct
distal convoluted tubule
descending loop of Henle
question
proximal convoluted tubule
answer
Which structure is highlighted?
descending loop of Henle
proximal convoluted tubule
ascending loop of Henle
distal convoluted tubule
question
cortical nephron
answer
Which structure is highlighted?
cortical nephron
renal corpuscle
proximal convoluted tubule
juxtamedullary nephron
question
efferent arterioles
answer
Which blood vessels are highlighted?
afferent arterioles
cortical radiate vessels
arcuate vessels
efferent arterioles
question
filtration
answer
Which of the following functions is associated with the highlighted structure?
active transport
reabsorption
filtration
secretion
question
Interlobar vessels
answer
Which blood vessels are highlighted?
interlobar
cortical radiate
renal
arcuate
question
ascending loop of Henle
answer
Which structure is highlighted?
cortical nephron
collecting duct
juxtamedullary nephron
ascending loop of Henle
question
prostatic urethra
answer
Which structure is highlighted?
membranous urethra
ureter
spongy urethra
prostatic urethra
question
medulla
answer
The highlighted structures (Renal pyramids) are within which region of the kidney?
medulla
transitional epithelium
cortex
capsule
question
spongy urethra
answer
Which structure is highlighted?
ureter
prostatic urethra
membranous urethra
spongy urethra
question
urinary bladder
answer
Which structure is highlighted?
ureter
urinary bladder
prostatic urethra
spongy urethra
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