Which of the following is NOT a function of the kidneys?
regulation of plasma temperature
regulation of plasma osmolarity
regulation of plasma ionic concentration
regulation of plasma hydrogen concentration
regulation of plasma volume
answer
regulation of plasma temperature
question
The primary function of the kidneys involves regulating the ________ and the ________ of plasma and interstitial fluid.
temperature : composition
temperature : composition
volume : temperature
volume : composition
composition : osmolarity
answer
volume:composition
question
Once produced, urine travels through the ________ until it reaches the bladder, from which it is released into the external environment through the ________.
renal hilus : ureter
collecting duct : urethra
ureter : urethra
collecting duct : ureter
urethra : ureter
answer
ureter:urethra
question
What hormone is secreted by the kidneys to increase red blood cell synthesis?
vitamin D
renin
erythropoietin
ANP
angiotensin
answer
erythropoetin
question
What is the functional unit of the kidney?
proximal tubule
nephron
glomerulus
loop of Henle
collecting ducts
answer
nephron
question
What two structures make up the renal corpuscle?
proximal straight and proximal convoluted tubules
nephron and collecting duct
major and minor calyces
Bowman's capsule and glomerulus
afferent and efferent arterioles
answer
Bowman's capsule and glomerulus
question
Blood leaves the ________ and enters the glomerulus.
vasa recta
afferent arteriole
peritubular capillary
Bowman's capsule
efferent arteriole
answer
afferent arteriole
question
Where does blood leaving the glomerulus go next?
afferent arteriole
efferent arteriole
vasa recta
Bowman's capsule
peritubular capillary
answer
efferent arteriole
question
After fluid passes through the entire proximal tubule, the fluid will enter the
Bowman's capsule.
distal tubule.
connecting tubule.
collecting duct.
loop of Henle.
answer
loop of Henle
question
During what renal process are molecules selectively removed from the tubule lumen, moved into the interstitial space, and removed from the kidneys by the peritubular capillaries and the vasa recta?
absorption
secretion
filtration
excretion
reabsorption
answer
reabsorption
question
What structure filters the blood to regulate its composition?
liver
ureter
kidneys
bladder
urethra
answer
kidneys
question
What structure stores urine prior to micturition?
urethra
ureter
liver
kidneys
bladder
answer
bladder
question
What structure transports urine from the kidneys to the bladder?
urethra
bladder
kidneys
liver
ureter
answer
ureter
question
What structure transports urine from the bladder to outside of the body?
kidneys
ureter
bladder
liver
urethra
answer
urethra
question
Which of the following describes movement from glomerular capillaries into Bowman's capsule?
secretion
filtration
micturation
excretion
reabsorption
answer
Filtration
question
Which of the following describes movement from renal tubules into the peritubular capillaries?
secretion
excretion
micturation
filtration
reabsorption
answer
reabsorption
question
Which of the following conditions might lead to glucose levels exceeding the transport maximum in the proximal tubules?
diabetes mellitus
dehydration
kidney stones
diabetes insipidus
answer
diabetes mellitus
question
What is the process whereby protein-free plasma moves by bulk flow from the glomerulus into Bowman's capsules?
secretion
glomerular filtration
excretion
absorption
reabsorption
answer
glomerular filtration
question
Which of the following forms the filtration barrier?
capillary endothelial cells only
podocytes only
basement membrane only
both capillary endothelial cells and basement membrane
capillary endothelial cells, basement membrane, and podocytes
answer
capillary endothelial cells, basement membrane and podocytes
question
In which portion of the nephron are glucose and amino acids reabsorbed?
descending limb of the loop of Henle
ascending limb of the loop of Henle
distal tubule
proximal tubule
answer
proximal tubule
question
A person must void what volume of urine per day?
0 mL
15 mL
120 mL
440 mL
1200 mL
answer
440 mL
question
From where is ADH released?
posterior pituitary
pancreas
anterior pituitary
collecting duct
distal tubule
answer
posterior pituitary
question
Antidiuretic hormone binds to receptors on ________ cells in the collecting ducts and distal tubules where it ________.
intercalated : causes vesicles with aquaporin-3 to insert into the apical membrane
granular : causes vesicles with aquaporin-2 to insert into the apical membrane
intercalated : causes vesicles with aquaporin-2 to insert into the basolateral membrane
principal : causes insertion of aquaporin-2 into the apical membrane
principal : causes vesicle with aquaporin-3 to insert into the apical membrane
answer
principal : causes insertion of aquaporin-2 into the apical membrane
question
The activity of the respiratory system can increase pH by
a hyperventilation-induced decrease in PCO2.
a hypoventilation-induced decrease in PCO2.
a hypoventilation-induced increase in PCO2.
a hyperventilation-induced increase in PCO2.
increasing the amount of carbonic acid in the blood.
answer
a hyperventilation-induced decrease in PCO2.
question
A person walks into the emergency room with rapid and shallow breathing and a feeling of light-headedness. A blood test shows high levels of bicarbonate ions and a pH of 7.34. What could explain these symptoms?
metabolic acidosis with respiratory compensation
respiratory acidosis with renal compensation
respiratory alkylosis with renal compensation
acidosis with no compensation
metabolic alkylosis with respiratory compensation
answer
respiratory acidosis with renal compensation
question
Which statement BEST distinguishes metabolic acidosis from respiratory acidosis?
Metabolic acidosis occurs due to changes in bicarbonate as opposed to PCO2.
Metabolic acidosis is a disturbance in blood pH caused by exercise as opposed to hyper- or hypoventilation.
Metabolic acidosis is a disturbance in blood pH caused by something other than an abnormal PCO2.
Metabolic acidosis occurs due to changes in blood glucose as opposed to changes in Po2 and PCO2.
Metabolic acidosis occurs due to changes in PO2 as opposed to PCO2.
answer
Metabolic acidosis is a disturbance in blood pH caused by something other than abnormal PCO2.
question
During hyperventilation, why do some people detect a tingling sensation in their hands and feet?
a decrease in blood flow to the distal extremities
hyperexcitability of afferent neurons
widespread release of catecholamines
an increase in carbon dioxide in blood
a decrease in carbon dioxide in blood
answer
hyperexcitability of afferent neurons
question
Which of the following is NOT a metabolic disturbance that can result in a metabolic acidosis?
heavy exercise
high-fat diet
high-protein diet
severe diarrhea
excessive vomiting
answer
excessive vomiting
question
What is the most rapid defense against changes in blood pH?
renal compensation
cardiac compensation
respiratory compensation
hepatic compensation
buffering of hydrogen ions
answer
buffering of hydrogen ions
question
How does severe diarrhea cause a metabolic acidosis?
loss of hydrogen ions
production of hydrogen ions
production of bicarbonate
loss of bicarbonate
loss of phosphate
answer
loss of bicarbonate
question
How does severe vomiting cause a metabolic alkalosis?
loss of phosphate
production of hydrogen ions
loss of bicarbonate
production of bicarbonate
loss of hydrogen ions
answer
loss of hydrogen ions
question
How might a high-protein diet cause metabolic acidosis?
loss of phosphate
production of phosphoric acid and sulfuric acid
loss of bicarbonate
direct production of hydrogen ions
loss of hydrogen ions
answer
production of phosphoric acid and sulfuric acid
question
How might heavy exercise cause metabolic acidosis?
loss of bicarbonate
production of lactic acid
loss of phosphate
loss of hydrogen ions
direct production of hydrogen ions
answer
production of lactic acid
question
How might a high-fat diet cause metabolic acidosis?
breakdown of fat into fatty acids
loss of phosphate
loss of bicarbonate
loss of hydrogen ions
direct production of hydrogen ions
answer
breakdown of fat into fatty acids
question
Which of the following acts as a buffer to minimize changes in intracellular pH?
answer
phosphate
question
The role of a buffer is to
enhance the ability of an increase in hydrogen ions to increase pH.
reduce the secretion of hydrogen ions in the kidneys.
reduce the secretion of bicarbonate ions in the kidneys.
reduce the reabsorption of hydrogen ions in the kidneys.
limit the change in pH with changing hydrogen ion concentrations.
answer
limit the change in Ph with changing hydrogen ion concentrations.
question
What is the secondary defense against changes in pH that requires minutes to be activated?
buffering of hydrogen ions
renal compensation
hepatic compensation
respiratory compensation
cardiac compensation
answer
respiratory compensation
question
Respiratory compensation for changes in pH is originated by
central chemoreceptors.
directly affecting the activity of the diaphragm.
baroreceptors.
peripheral chemoreceptors.
proprioceptors.
answer
peripheral chemoreceptors
question
When an increase in hydrogen ions remains after one hour, this will lead to a(n)
decrease in bicarbonate reabsorption in the kidneys.
increased hydrogen reabsorption in the kidneys.
failure of the kidneys to filter any more hydrogen ions.
increase in hydrogen ion secretion from the kidneys.
increase in bicarbonate secretion in the kidneys.
answer
increase in hydrogen ion secretion from the kidneys
question
If hydrogen ions are added to a solution, the pH will
increase.
decrease.
remain the same.
answer
decrease
question
In order to compensate for a hyperventilation, the
kidneys decrease the reabsorption of bicarbonate.
lungs increase ventilation rate.
kidneys increase the reabsorption of hydrogen ions.
kidneys increase the secretion of hydrogen ions.
kidneys increase the conversion of glutamine to bicarbonate.
answer
kidneys decrease the reabsorption of bicarbonate
question
What is internal respiration?
exchange of oxygen and carbon dioxide at the tissue level
exchange of oxygen between the atmosphere and lungs
the binding of oxygen to hemoglobin
mitochondrial use of oxygen to produce energy
answer
mitochondrial use of oxygen to produce energy
question
What is external respiration?
mitochondrial use of oxygen to produce energy
the binding of oxygen to hemoglobin
exchange of oxygen between the atmosphere and lungs
exchange of oxygen and carbon dioxide at the tissue level
answer
exchange of oxygen between the atmosphere and lungs
question
Which of the following specifically describes the movement of air into and out of the lungs?
secondary ventilation
pulmonary ventilation
respiration
internal respiration
expiration
answer
pulmonary ventilation
question
Which of the following processes is NOT a part of external respiration?
the exchange of oxygen and carbon dioxide between the lungs and blood by diffusion
the use of oxygen and generation of carbon dioxide by the mitochondria during energy metabolism
the movement of air into and out of the lungs by bulk flow
the transportation of oxygen and carbon dioxide between the lungs and body tissues by the blood
the exchange of oxygen and carbon dioxide between the blood and tissues by diffusion
answer
the use of oxygen and generation of carbon dioxide by the mitochondria during energy metabolism.
question
Which of the following is NOT a function of the respiratory system?
enhancing venous return
acid-base balance of blood
vocalization
electrolyte balance of blood
heat loss
answer
electrolyte balance of blood
question
Which of the following processes does NOT form part of external respiration?
pulmonary ventilation
transport of gases
Krebs cycle
gas exchange
answer
Kreb's cycle
question
Internal respiration refers to the use of oxygen and production of carbon dioxide by cells.
True
False
answer
True
question
What constitutes the upper airways?
the air passages prior to the lungs
the air passages from the nose and mouth through the conducting zone
the air passages of the head and neck
the air passages prior to the trachea
answer
the air passages of the head and neck
question
The conducting zone starts with the larynx. What specific function of the respiratory system is this organ specialized for?
defense against pathogens and foreign particles in the airway
humidification of air entering the lungs
vocalization
respiration
answer
vocalization
question
Where does gas exchange occur in the lungs?
goblet cells
alveoli
respiratory bronchioles
larynx
answer
alveoli
question
Which of the following is true of the pulmonary pressures?
Intrapleural pressure is always positive so that the pleural membranes remain in contact.
Because of pneumothorax, intrapleural pressure equilibrates with atmospheric pressure. Without the positive force of alveolar pressure pushing the lung outward, the lung collapses due to elastic recoil forces.
The difference between intra-alveolar pressure and atmospheric pressure is the pressure gradient that drives ventilation.
An increase in transpulmonary pressure creates a larger collapsing pressure across the lungs, which is accompanied by the contraction of the lungs (alveoli).
answer
The difference between intra-alveolar pressure and atmospheric pressure is the pressure gradient that drives ventilation.
question
When air is no longer moving through the respiratory tract and the airway is open to the environment, the pressure within the lung is equal to
intrapleural pressure.
end-diastolic pressure.
atmospheric pressure.
systolic blood pressure.
transpulmonary pressure.
answer
atmospheric pressure
question
Which alveolar cells engulf foreign particles and pathogens inhaled into the lungs?
alveolar type I cells
goblet cells
alveolar macrophages
alveolar type II cells
answer
alveolar macrophages
question
The difference between what two pressures drives air into and out of the lungs?
intrapleural and intra-alveolar
central venous and intracoronary
pulmonary venous and atmospheric
atmospheric and intrapleural
atmospheric and intra-alveolar
answer
atmospheric and intra-alveolar
question
In a mixture of gases, the driving force for the movement of an individual gas within that mixture is ultimately the
volume of the gas.
solubility of the gas.
total pressure of the gases.
partial pressure of that gas.
fractional concentration of that gas.
answer
partial pressure of that gas
question
What is the most abundant gas in the air that we breathe?
carbon dioxide
hydrogen
water vapor
nitrogen
oxygen
answer
nitrogen
question
What percentage of air is oxygen?
79%
< 1%
12%
21%
6%
answer
21%
question
Which organ of the GI absorbs water and ions?
ileum
the colon
stomach
the duodenum
answer
the colon
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