Chapter 26: Fluid, Electrolyte, And Acid-Base Balance

24 July 2022
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question
In which compartment of the body is the majority of water stored? a.) plasma b.) intracellular fluid (ICF) compartment c.) extracellular fluid (ECF) compartment d.) interstitial fluid (IF)
answer
B ( The intracellular fluid (ICF) compartment holds 40% of the body's water, making it the largest of the three compartments.)
question
If the osmotic pressure of the blood were increased above normal levels, which of the following volumes would also increase? a.) interstitial fluid volume b.) blood volume c.) total body water d.) intracellular fluid volume
answer
B (blood volume. The higher osmotic pressure in the blood would draw water from the interstitial fluid, resulting in a higher blood volume and increased blood hydrostatic pressure.)
question
What is the most abundant intracellular cation?
a.) K+
b.) Na+
c.) HPO42-
d.) Cl-
What is the most abundant intracellular cation? a.) K+ b.) Na+ c.) HPO42- d.) Cl-
answer
A (K+ is the most abundant cation in the intracellular fluid.)
question
Which of the following statements about fluid movement is NOT correct? a.) Exchanges between plasma and interstitial fluid happen between capillary walls. b.) Under normal circumstances, lymph vessels help maintain fluid balance, especially between the plasma and the interstitial fluid. c.) Exchange between interstitial fluid and intracellular fluid occurs across the plasma membrane. d.) Exchange between the plasma and the intracellular fluid occurs across the cell membrane.
answer
D (Exchange between the plasma and the intracellular fluid occurs across the cell membrane. Exchange between the plasma and the intracellular fluid would have to involve exchange through the interstitial fluid.)
question
What compound in body fluids adds to the fluids' electrical conductivity? a.) lipids b.) glucose c.) urea d.) sodium
answer
D (sodium. Sodium is an electrolyte--electrolytes are so named because they can create electrical currents in the body fluids.)
question
Mrs. M has suffered for many years from ulcerative colitis, a disease in which ulcers and scar tissue form in the lining of the intestine, usually affecting the ileum and/or colon. About a half-hour after eating a large meal, she became acutely ill with a distended abdomen and low blood pressure and finally collapsed. She was brought into the emergency room and diagnosed with a bowel obstruction caused by scar tissue blocking her large intestine. The ER doctor said this obstruction caused a decrease in her blood volume. How could an obstructed bowel make blood volume decrease? This is a matter of osmosis. Normally, when a person eats food, the amount of solutes inside the bowel increases. Q- When Mrs. M ate, her intestinal contents became __________ to her blood. Her blood became __________ to her intestinal contents. a.) isoosmotic pressure, hyperosmotic pressure b.) hyperosmotic pressure, hypoosmotic pressure c.) hypoosmotic pressure, hyperosmotic pressure d.) hyperosmotic pressure, isoosmotic pressure e.) isoosmotic pressure, hypoosmotic pressure
answer
B (hyperosmotic pressure, hypoosmotic pressure. You are right. Filling the intestines with food raised the concentration of solutes in her intestinal contents, making them hyperosmotic pressure to her blood.)
question
After treatment with intravenous fluids, Mrs. M. is feeling better and is able to talk with her doctor. She tells you she has finally agreed to have a colostomy − an operation in which part of her large intestine is removed, leaving an opening on her abdomen (a stoma) where the intestinal contents are emptied into a colostomy bag. She refused this operation for years because her aunt had an ileostomy and struggled with fluid balance and managing her ileostomy bag. In Mrs. M's aunt's ileostomy, all of the large intestine was removed. In Mrs. M's colostomy, only part of the large intestine will be removed. How will water balance be different in patients with an ileostomy versus a colostomy? Choose the best answer. a.) Patients with an ileostomy will have more problems with water balance because they have less intestinal surface to absorb solutes into the blood. b.) They will have the same kind of problems with water balance because both have had part of their intestines removed. c.) Patients with a colostomy will have more problems with water balance because they have more intestinal surface to absorb solutes into the blood.
answer
A (Patients with an ileostomy will have more problems with water balance because they have less intestinal surface to absorb solutes into the blood. The large intestine absorbs solutes from the intestinal contents into the blood, and water follows the solutes. If the entire large intestine is removed (ileostomy), the discharge into the patient's ostomy bag will contain lots of unabsorbed solutes and water and will be very fluid. If only part of the colon is removed (colostomy), the discharge will be less watery and more like regular stools, because more solutes and water have been absorbed from the intestinal contents into the blood. This means that clients with ileostomies will have a bigger problem remaining hydrated. )
question
What would be an appropriate concentration of intravenous (IV) saline to give a patient suffering from severe water intoxication? a.) 0.01% b.) 0.90% c.) 3.00% d.) 0.45%
answer
C (3%)
question
Which of the following is NOT a hormone involved in water and electrolyte balance? a.) thyroxine b.) atrial natriuretic peptide c.) aldosterone d.) ADH
answer
A (thyroxine. Thyroxine is not involved in water and electrolyte balance.)
question
What is the driving force for water intake? a.) aldosterone b.) ADH c.) thirst d.) glucose concentration
answer
C (thirst)
question
In a typical day, what amount of water is taken by mouth? a.) 250 milliliters b.) 750 milliliters c.) 1500 milliliters d.) 2250 milliliters
answer
D (2250ml The combined volume of water from food (750 milliliters) and beverages (1500 milliliters) is 2250 milliliters.)
question
Which of the following statements is FALSE regarding water intake and output by the body? a.) An increase in fluid taken by mouth would reduce the amount produced by metabolism. b.) The proportion of fluid lost by the body as sweat would increase during exercise. c.) An increase in the amount of beverages taken by mouth would increase the urine output. d.) An irritation to the colon that leads to diarrhea would increase the proportion of water lost through feces.
answer
A (An increase in fluid taken by mouth would reduce the amount produced by metabolism. The water produced by metabolism is a by-product of energy processing. This amount is not dependent on the amount of water taken by mouth.)
question
Where are signs of change in osmolality, stomach stretch, and thirst monitored? a.) in the kidneys b.) in the hypothalamus c.) in the adrenal glands d.) in the stomach and intestines
answer
B (hypothalamus. Centers for detecting osmolarity changes and other signs of water balance are in the hypothalamus.)
question
What type of water imbalance increases the amount of fluid in all compartments?
a.) inflammation 
b.) hypotonic hydration 
c.) edema 
d.) dehydration
What type of water imbalance increases the amount of fluid in all compartments? a.) inflammation b.) hypotonic hydration c.) edema d.) dehydration
answer
B (hypotonic hydration. Hypotonic hydration occurs when extracellular fluid becomes so hypotonic (dilute) that water is pulled into the cells. Excess water is present in cells, intracellular compartments, and extracellular compartments.)
question
Which of the following would NOT be expected to occur as a result of dehydration?
a.) reduced urine flow 
b.) edema 
c.) hypovolemic shock 
d.) shrinkage of body cells
Which of the following would NOT be expected to occur as a result of dehydration? a.) reduced urine flow b.) edema c.) hypovolemic shock d.) shrinkage of body cells
answer
B (edema. Edema is tissue swelling that results from an atypical accumulation of fluid in the interstitial space. During dehydration, this fluid would be reduced.)
question
The role of ADH is to __________. a) decrease water reabsorption b.) increase water reabsorption c.) produce dilute urine d.) lower blood pressure
answer
B (increase water reabsorption. ADH increases water reabsorption at the collecting ducts in the kidneys.)
question
Which of the following would NOT be expected to lead to edema? a.) hyponatremia b.) inflammation c.) hypoproteinemia d.) incompetent venous valves
answer
A (hyponatremia. Hyponatremia is low levels of sodium in the blood. This can lead to dehydration, not edema.)
question
Which of the following is NOT a risk factor for dehydration? a.) increased muscle mass b.) inefficient kidneys c.) a high rate of insensible water loss d.) vomiting
answer
A (increased muscle mass. Aerobic metabolism of glucose in muscle tissue would actually generate water for the body.)
question
Which of the following is not an electrolyte? a.) salt b.) acid c.) base d.) carbohydrate
answer
D (carbohydrates. Excellent! Carbohydrates are held together by covalent bonds, whereas electrolytes are held together by ionic bonds.)
question
Which of the following is true of electrolytes? a.) They do not dissolve in water. b.) They are ionic compounds. c.) They are produced from water. d.) They are held together by covalent bonds.
answer
B (They are ionic compounds. Electrolytes dissociate, or come apart, in water, releasing ions, which have electrical charges—hence the term "electrolyte.")
question
The adrenal glands of a patient with primary aldosteronism produce too much aldosterone, causing a loss of potassium and subsequent hypokalemia. What electrolyte is retained by the kidneys when potassium is lost? a.) magnesium b.) sodium c.) bicarbonate d.) chloride
answer
B (sodium)
question
How does severe hyperkalemia negatively affect the heart? a.) reduces depolarization events b.) increases SA node firing c.) promotes tachycardia d.) increases cardiac output
answer
A (reduces depolarization events)
question
A friend has acid indigestion after eating a big meal. Which of the following would act as a buffer and help ease his pain? a.) milk of magnesia, with a pH of 10 b.) cola, with a pH of 3 c.) black coffee, with a pH of 5 d.) pure water, with a pH of 7
answer
A (Excess acid can be buffered by the addition of an alkaline or base.)
question
If a person exercises for a long time, lactic acid will start to build up in his or her muscles. Which of the following would you expect to happen as the lactic acid first starts to be formed? a.) More water will move to the muscles to buffer the acid. b.) Weak bases in the muscles will act as buffers and resist or minimize any pH change. c.) Weak acids in the muscles will act as buffers and resist or minimize any pH change. d.) More water will move to the muscles to move out the acid.
answer
B (Weak bases in the muscles will act as buffers and resist or minimize any pH change.)
question
Of the three buffering mechanisms in the body, which is the strongest? a.) chemical buffer system b.) renal system c.) respiratory system
answer
B (renal system. Yes, although slow, the renal system is the strongest buffering system in the body. By altering the reabsorption and excretion of hydrogen ions and bicarbonate ions, the kidneys control the pH of body fluids.)
question
The bicarbonate buffer system is one of the chemical buffer systems of the body. How would the bicarbonate buffer system work if sodium hydroxide were added to a solution? a.) The hydrogen ion would attach to carbonic acid. b.) A hydrogen on carbonic acid would dissociate and join the hydroxyl group on the base to form water and sodium bicarbonate. c.) The hydrogen ion would attach to bicarbonate (HCO3) to form carbonic acid (H2CO3).
answer
B (A hydrogen on carbonic acid would dissociate and join the hydroxyl group on the base to form water and sodium bicarbonate.)
question
The respiratory system is one of the three systems that regulate acid-base balance in the body. How does it work to decrease an acidosis? a.) Carbonic acid is converted to bicarbonate, which then buffers the acid. b.) Carbonic acid is broken down into water and CO2; the CO2 is then exhaled. c.) Carbonic acid converts a strong acid to a weak acid, thus decreasing acidity. d.) Carbonic acid is converted to bicarbonate and hydrogen ions.
answer
B (Carbonic acid is broken down into water and CO2; the CO2 is then exhaled.)
question
In a respiratory acidosis the kidney would do which of the following? a.) The kidney would increase excretion of both bicarbonate and hydrogen ions. b.) The kidney will reabsorb both bicarbonate and hydrogen ions. When it reabsorbs the hydrogen ion, it also generates more bicarbonate ions. c.) The kidney would reabsorb bicarbonate and secrete hydrogen ions.
answer
C (The kidney would reabsorb bicarbonate and secrete hydrogen ions. when the kidney secretes hydrogen ions it also generates a bicarbonate ion, which further aids in decreasing the acidity of the plasma.)
question
Ingesting too much antacid would cause which of the following acid-base disturbances? a.) metabolic alkalosis b.) metabolic acidosis c.) respiratory acidosis d.) respiratory alkalosis
answer
A (metabolic alkalosis. ingestion of an antacid would increase the bicarbonate, causing a metabolic alkalosis.)
question
Vomiting will cause which type of acid-base disturbance? a.) respiratory acidosis b.) respiratory alkalosis c.) metabolic alkalosis d.) metabolic acidosis
answer
C (metabolic alkalosis. loss of HCL acid from the stomach would cause a metabolic alkalosis.)
question
Severe anxiety would cause which type of acid-base disturbance? What would be the compensation? a.) respiratory acidosis; kidneys would excrete HCO3 b.) respiratory alkalosis; kidneys would retain HCO3 c.) metabolic alkalosis; hypoventilation by the lungs d.) respiratory alkalosis; kidneys would excrete HCO3
answer
D (respiratory alkalosis; kidneys would excrete HCO3. during hyperventilation caused by severe anxiety, carbonic acid is excreted from the lungs in the form of CO2, thus causing an alkalosis. Kidneys would compensate by excreting HCO3.)
question
Starvation would cause which of the following acid-base conditions? Also, determine what type of compensation (metabolic or respiratory) there would be. a.) metabolic alkalosis with respiratory compensation b.) respiratory acidosis with metabolic compensation c.) respiratory alkalosis with metabolic compensation d.) metabolic acidosis with respiratory compensation
answer
D (metabolic acidosis with respiratory compensation. this is known as a ketosis (due to the breakdown of fat for metabolism), and the respiratory system would increase respiration to compensate for the excess hydrogen ions.)
question
A patient is admitted to the hospital with the following plasma values: pH = 7.2, pCO2 = 55 mmHg, and HCO3¯ = 30 mEq/L. What is the acid base imbalance? a.) metabolic alkalosis with respiratory compensation b.) metabolic acidosis with respiratory compensation c.) respiratory alkalosis with metabolic compensation d.) respiratory acidosis with metabolic compensation
answer
D (respiratory acidosis with metabolic compensation. Since pCO2 is above the normal range, it is the cause of the acidosis. HCO3 is increased to compensate, which is a metabolic compensation.)
question
A patient is admitted to the hospital with the following plasma values: pH = 7.5, pCO2 = 45 mmHg, and HCO3¯ = 30 mEq/L. What is the acid-base imbalance? a.) respiratory alkalosis with metabolic compensation b.) respiratory acidosis with metabolic compensation c.) metabolic alkalosis with no compensation d.) metabolic alkalosis with respiratory compensation
answer
C (metabolic alkalosis with no compensation. since HCO3¯ is 30 (above the normal range of 22 to 26 mEq/L), this is definitely a metabolic alkalosis. There is no respiratory compensation since CO2 is within the normal range.)
question
A patient is admitted to the hospital with the following plasma values: pH = 7.2, pCO2 = 25 mmHg, and HCO3¯ = 18 mEq/L. What is the acid base imbalance? a.) respiratory acidosis with metabolic compensation b.) metabolic alkalosis with respiratory compensation c.) metabolic acidosis with respiratory compensation d.) metabolic acidosis with no compensation
answer
C (metabolic acidosis with respiratory compensation. the low bicarbonate indicates this is a metabolic acidosis. Since CO2 is below the normal range, this indicates there is a respiratory compensation.)
question
Diarrhea can lead to which acid/base disturbance? Assuming compensation, would it be a metabolic or respiratory compensation? a.) respiratory acidosis with metabolic compensation b.) metabolic acidosis with respiratory compensation c.) respiratory alkalosis with metabolic compensation d.) metabolic alkalosis with respiratory compensation
answer
B (metabolic acidosis with respiratory compensation. with the loss of bicarbonate ions, this is a metabolic acidosis. If compensated, it would be a respiratory compensation.)
question
Emphysema can lead to which acid/base disturbance? What would be the compensation? a.) respiratory alkalosis; kidneys will retain more H+ and excrete HCO3 b.) respiratory acidosis; hyperventilation c.) respiratory acidosis; kidneys will retain more HCO3 and excrete H+ d.) metabolic acidosis; hypoventilation by the lungs
answer
C (respiratory acidosis; kidneys will retain more HCO3 and excrete H+. a patient with emphysema would retain CO2, leading to a respiratory acidosis. The kidneys would compensate by retaining HCO3 and excreting H+.)
question
What is the most important trigger for aldosterone release? a.) decreased sodium ion concentration in the extracellular fluids (ECF) b.) decreased K+ concentration in the extracellular fluids (ECF) c.) increased osmolality of the extracellular fluids (ECF) d.) renin-angiotensin-aldosterone mechanism
answer
D (renin-angiotensin-aldosterone mechanism. Renin release from the kidney and subsequent activation of angiotensin is the most important trigger for aldosterone release.)
question
Which of the following does NOT impact how much sodium is reabsorbed? a.) atrial natriuretic peptide b.) aldosterone c.) estrogen d.) transport maximum of the renal proximal tubule
answer
D (transport maximum of the renal proximal tubule. The transport maximum only describes the max potential for sodium transport. This transport is regulated by hormones that influence transport, especially beyond the proximal convoluted tubule (PCT).)
question
A patient is discovered to have a strange craving for iron objects. To try to determine the cause, her physician decides to order tests to determine if this patient might have some type of ______. a.) hypothyroidism b.) diabetes c.) acidosis d.) anemia
answer
D (anemia. Anemia is a condition where red blood cells have an abnormally low oxygen carrying capacity. This capacity depends on the iron content within the hemoglobin molecule.)
question
Hypersecretion of aldosterone results in hypokalemia, which causes hyperpolarization of neurons; this in turn results in ______. a.) increased speed of sodium-potassium pump activity in order to compensate for the reduced concentration of potassium ions b.) decreased plasma membrane permeability to potassium ions c.) the need for a stronger than normal stimulus in order to trigger an action potential d.) a craving for more salt in the diet
answer
C (the need for a stronger than normal stimulus in order to trigger an action potential. To trigger an action potential cells must reach threshold (critical electrical value required to open voltage-gated ion channels). If the membrane potential is hyperpolarized and falls below normal resting membrane potential, then more cations must enter the cytoplasm for the cell to reach threshold.)
question
The most important renal mechanism for regulating acid-base balance of the blood involves __________. a.) maintaining CO2 balance b.) maintaining HCO3- balance c.) maintaining water balance d.) maintaining phosphate balance
answer
B (maintaining HCO3- balance. Excretion of bicarbonate is a long-term mechanism that the kidneys contribute to acid-base regulation.)
question
This chemical equation shows the reaction of a strong acid and weak base in the bicarbonate buffer system. Provide the products of the following reaction. HCl + NaHCO3 → a.) H2CO3 + NaCl b.) NaH2PO4 + NaCl c.) NaOH + NaH2PO4 d.) NaHCO3 + H2O
answer
A (H2CO3 + NaCl . HCl is a strong acid and will completely dissociate in water, as will the salt NaHCO3. The bicarbonate ion will bond to the free hydrogen ion forming carbonic acid, while the remaining ions will form aqueous salt (NaCl).)
question
Which of the following does NOT serve as a source of acids in the body? a.) aerobic breakdown of glucose b.) CO2 in the blood c.) fat metabolism d.) ingesting of bicarbonate
answer
D (ingesting of bicarbonate.)
question
In order to buffer a strong acid into a weak acid, which has a less dramatic effect on pH, what chemical should be used as the buffer? a.) a weak base b.) water c.) a weak acid d.) salt
answer
A (a weak base. Weak bases have an affinity for hydrogen ions in water and, by binding them, reduce their effects on pH.)
question
An increase in blood CO2 levels leads to __________. a.) an increase in blood pH b.) a decreased respiratory rate c.) a drop in blood pH d.) a decrease in carbonic acid
answer
C (a drop in blood pH. An increase in CO2 results in the formation of more carbonic acid, which leads to an increase in acidity, or a drop in pH.)
question
Which of the following blood workups would most likely demonstrate metabolic acidosis? a.) pH: 7.33; PCO2: 50 mmHg; HCO3-: 30 mEq/L b.) pH: 7.55; PCO2: 30 mmHg; HCO3-: 20 mEq/L c.) pH: 7.50; PCO2: 50 mmHg; HCO3-: 30 mEq/L d.) pH: 7.33; PCO2: 30 mmHg; HCO3-: 20 mEq/L
answer
D (pH: 7.33; PCO2: 30 mmHg; HCO3-: 20 mEq/L. The pH indicates acidosis, but the PCO2 is low. The cause is not likely to be respiratory acidosis. The HCO3- concentration indicates that the cause here would be metabolic acidosis.)
question
Which acid-base imbalance would be caused by overaccumulation of CO2 in the blood? a.) respiratory acidosis b.) metabolic alkalosis c.) respiratory alkalosis d.) metabolic acidosis
answer
A (respiratory acidosis. Respiratory acidosis occurs during periods of hypoventilation. This allows CO2 to build up in the lungs, lowering blood pH and increasing PCO2.)
question
What is the effect of hypoventilation on pH? a.) respiratory acidosis b.) metabolic acidosis c.) respiratory alkalosis d.) metabolic alkalosis
answer
A (respiratory acidosis. Hypoventilation causes decreased CO2 exhalation. With higher blood CO2, there is more carbonic acid formed, so the patient goes into acidosis.)
question
What is the normal range for the partial pressure of carbon dioxide in the blood? a.) 55 - 65 mm Hg b.) 15 - 25 mmHg c.) 35 - 45 mm Hg d.) 7.35 - 7.45 mm Hg
answer
C (38-42 actually)
question
Hyperventilation can result in _______. a.) too little carbon dioxide in the blood b.) too much oxygen in the blood c.) too much carbon dioxide in the blood d.) respiratory acidosis
answer
A (too little carbon dioxide in the blood)
question
Why was the breath held after the second hyperventilation? a.) to retain oxygen b.) to absorb water c.) to retain carbon dioxide d.) to absorb H+
answer
C (to retain carbon dioxide)
question
Respiratory acidosis can be a result of _______. a.) a panic attack b.) hyperventilation c.) hyperventilation and a panic attack d.) asthma and hyperventilation e.) asthma
answer
E (asthma)
question
Which of the following occurred during rebreathing? a.) hyperventilation, carbon dioxide increased and pH increased b.) hyperventilation c.) carbon dioxide increased d.) pH increased
answer
C (carbon dioxide increased)
question
Respiratory acidosis can be compensated for by _______. a.) hypoventilation and rebreathing b.) hypoventilation c.) hyperventilation d.) rebreathing e.) the kidneys
answer
E (the kidneys)
question
Carbon dioxide levels in the blood and blood pH are _______. a.) directly proportional to the amount of oxygen b.) directly proportional to each other c.) independent of each other d.) inversely proportional to each other
answer
D (inversely proportional to each other)
question
The kidneys compensate for respiratory alkalosis by _______. a.) conserving bicarbonate ion and excreting H+ b.) conserving H+ and excreting bicarbonate ion c.) conserving H+ and bicarbonate ion d.) excreting H+ and bicarbonate ion
answer
B (conserving H+ and excreting bicarbonate ion)
question
In uncompensated respiratory acidosis, the _______. a.) carbon dioxide levels of the blood are elevated b.) pH of the blood is high c.) carbon dioxide levels of the blood are low d.) carbon dioxide level of the blood is normal
answer
A (carbon dioxide levels of the blood are elevated)
question
When the partial pressure of carbon dioxide was decreased, what changes occurred in the urine? a.) H+ and bicarbonate ion both increased in the urine. b.) H+ in the urine decreased and bicarbonate ion increased in the urine. c.) H+ in the urine increased and bicarbonate ion decreased in the urine. d.) H+ and bicarbonate ion both decreased in the urine.
answer
B (H+ in the urine decreased and bicarbonate ion increased in the urine.)
question
At which partial pressure of carbon dioxide did respiratory acidosis occur? a.) 60 mm Hg b.) 40 mm Hg c.) 30 mm Hg d.) 30 mm Hg, 40 mm Hg and 60 mm Hg
answer
A (60 mm Hg)
question
Compensation of metabolic alkalosis includes which of the following? a.) excreting bicarbonate ion in the renal system and retaining carbon dioxide through the respiratory system b.) conserving bicarbonate ion in the renal system and retaining carbon dioxide through the respiratory system c.) conserving bicarbonate ion in the renal system d.) excreting bicarbonate ion in the renal system e.) retaining carbon dioxide through the respiratory system
answer
A (excreting bicarbonate ion in the renal system and retaining carbon dioxide through the respiratory system)
question
Metabolic acidosis results in _______. a.) hypoventilation and rebreathing b.) rebreathing c.) hyperventilation d.) hypoventilation
answer
C (hyperventilation)