BIO222 Chapter 22 Mastery

25 July 2022
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If the thymus shrank and stopped making thymosins, we would expect to see an immediate decrease in the number of
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T cells
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Immunoglobulins that are most abundant and are responsible for resistance against many viruses, bacteria, and bacterial toxins are
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IgG
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Immunoglobulins that are found on the surface of B cells and that may activate antibody production are
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IgD
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Helper T cells do all of the following except: enhance nonspecific defenses. trigger B-cell division, plasma cell maturation, and antibody production. provide a rapid response to a future exposure to the antigen. attract macrophages to the affected area. enhance production of memory and cytotoxic T cells.
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provide a rapid response to a future exposure to the antigen.
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Cells that help regulate the immune response are ________ cells.
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helper T
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A substance that provokes an immune response is called an
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antigen
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The cells directly responsible for cellular immunity are the ________ cells.
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cytotoxic T
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An inflammatory response is triggered when
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mast cells release histamine and heparin.
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What feature do lymphatic vessels share with veins that allows lymph to flow in only one direction?
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valves
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The lymphoid organ that acts like a filter as lymph passes through is
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lymph nodes
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Lymph fluid enters the venous circulation via the
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subclavian veins
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Antigens that trigger allergic reactions are called
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allergens
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Which of the following is NOT an effect of glucocorticoid secretion on the effectiveness of the immune response?
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increased interferon activity
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interferons
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interfere with viral replication
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B cells are primarily activated by the activities of
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helper T cells
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The cells that perform immunological surveillance are the ________ cells.
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NK
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The process by which the surface of a microorganism is covered with antibodies and complement, rendering it more likely to be phagocytized, is called
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opsonization.
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The lymphatic system does all of the following except: fights infection. transports gases to and away from lymph nodes. eliminates variations in the composition of interstitial fluid. helps maintain normal blood volume. transports lipids from the digestive tract.
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transports gases to and away from lymph nodes.
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The process by which antibodies bind to the antigen on the surface of cells, forming large immune complexes, is called
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agglutination
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The first line of cellular defense against pathogens are the
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phagocytes
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Immunoglobulins that attach to and sensitize mast cells and basophils are
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IgE
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The cells responsible for the production of circulating immunoglobulins are ________ cells.
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plasma
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Histamine increases blood flow and vascular permeability. This would account for all of the following changes that occur during inflammation except: heat of the inflamed tissue. movement of defense proteins and cells into the interstitial space. swelling of the inflamed tissue. redness of the inflamed tissue. chemotaxis of phagocytes.
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chemotaxis of phagocytes.
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In order for a lymphocyte to respond to an antigen, the antigen must
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bind to specific receptors on the lymphocyte surface.
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Steps in antigen presentation include which of these?
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Phagocytic antigen-presenting cells engulf pathogens. Antigen fragments appear on the antigen-presenting cell's surface. Antigens are digested.
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Hormones that regulate the activity of B cells and T cells and enhance nonspecific defense are called
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interleukins.
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Innate defenses include all of the following EXCEPT: fever phagocytes destruction of abnormal cells by NK cells production of antibodies
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production of antibodies
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Which class of T lymphocyte is killed by the AIDS virus?
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helper T
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Class II MHC proteins are found on which of the following cell types?
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antigen-presenting cells
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Which class of MHC proteins presents exogenous antigens?
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class II MHC proteins
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Class I MHC proteins are recognized by which of the following cell types (that are destined to become T cells)?
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CD8
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Which of the following types of cells display protein fragments produced by the cancer within them?
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all nucleated cells
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Which major class of lymphocytes become cytotoxic T cells?
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CD8 cells
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All of the following are characteristics of adaptive defenses except: tolerance. versatility. specificity. memory. present at birth.
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present at birth.
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The primary function of the lymphatic system is
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defending the body against both external and internal threats.
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Immunoglobulins, formed of five subunits, that are the first antibodies to be produced in response to infection, are
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IgM
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When an antigen is bound to a Class I MHC molecule, it can stimulate a ________ cell.
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cytotoxic T
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When an antigen is bound to a Class II MHC protein, it can activate a ________ cell.
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helper T
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Each of the following is a physical barrier to infection except: epithelium. secretions. basement membranes. body hair. complement.
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complement
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Stress suppresses the immune response through the action of __________.
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glucocorticoids
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The cells responsible for humoral immunity are the ________ cells.
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B
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Lymph nodes do all of the following except: remove debris and pathogens from the lymph. accumulate cancer cells. remove excess nutrients from the lymph. monitor the contents of lymph. produce antibodies through B cells.
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remove excess nutrients from the lymph.
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The effects of activating the complement system include all of the following except: opsonization. chemotaxis. inhibition of the immune response. stimulation of inflammation. destruction of target cell plasma membranes.
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inhibition of the immune response.