Integumentary Medications

25 July 2022
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Antifungals
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Alter the cell wall of fungi or disrupt enzyme activity, resulting in death. Amphotercin B (Fungizone) Bethamethasone dipropionate, clotrimazole (Lotrisone) Circlopirox olamine (Loprox) Econazole nitrate (Spectazole) Haloprogrin Ketoconazole (Ketoderm) Miconazole (Micantin) Nystatin (Mycostatin) Tolnaftate (Tinactin) Triacetin Undecylenic acid (Desenex)
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Antiseptics
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Topically applied agents that inhibit growth of bacteria, thus preventing infectious in cuts, scratches, and surgical incisions. Sodium hypochlorite (Dankin's Solution) Chlorhexidine gluconate (Hibiclens) Acetic acid preps Hydrogen peroxide Hexacholorphene (pHisoHex, Septisol)
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Corticosteroids
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Decrease inflammation and itching by suppressing the immune system's inflammatory response to tissue damage. Hydrocortisone (Ceracort, Cartaid) Triamcinolone (Azmarcort, Kenalog)
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Keratolytics
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Destroy and soften the outer layer of skin so that it is sloughed off or shed. Cantharidin Imiquimod (Aldara) Masoprocol Podophyllum resin Podofilox (Codylox) Salicylic acid -*can be absored systemically causing salicylism (dizziness & tinnitus)
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Protectives
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Cover, cool, dry or soothe inflamed skin. TRANSPARENTS: Bio-occlusive membrane dressing OpSite Tegaderm HYDROCOLLOIDS: DuoDREM Tegasorb ALGINATES: Alginate Algosteril Comfeel BIOLOGICAL: AlloDerm Allograft Xenograft
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Emollients
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Soften, soothe irritated skin by allowing skin to return water. *Used for dry scaly, skin and itchy inflamed conditions. Cold cream Glycerin Lanolin Lubriderm Petrolatum Vitamin A&D Zinc Ointment
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Solutions and Lotions
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*They have a drying effect on the skin when the water evaporates. Aluminum acetate solution (Burow's solution) Calamine lotion (Caladryl lotion)
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Therapeutic Baths: Antipruritics Antibacterial Emollient baths Tar Baths
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Antipruritics: to relive itching -Aveeno collodial oatmeal -Aveeno oilated collidal oatmeal -Starch and baking soda Antibacterial: to reduce skin bacteria -Potassium permanganate Emollient baths: to clean skin and add moisture -Bath emollient (Alpha Keri Theraputic Bath oil) -bath oils -mineral oil Tar Baths: to loosen scaled skin and support ultraviolet A or B light therapy. -Coal Tar (Balnetar, Zetar shampoo) -Coal tar solution (Polytar soap and shampoo) -Other coal tar preparations
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Rubs and Liniments
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Used for temperary relief of muscular aches, rheumatism, arthritis, sprains, and neuralgia. Menthyl salicylate, menthol (Ben-Gay, Icy Hot) Trolamine salicylate (Aspercreame, Myoflex) *A heating pad is not used with these products because irritation/ burning of the skin may occur.
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Antibacterials
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Used for superficial skin infections. Bacitracin preps Cloramphenicol Chlortetracycline Erythromycin Gentamicin sulfate Neomycin preps Mupirocin calcium (Bactroban)-*topical against staph infections. appy 3xdaily. discontinue if no improvement within 3-5 days.
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Antivirals
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Inhibits DNA replication on the virus. Acyclovir (Zovirax) *use rubber gloves when applying ointment to prevent spread of infection.
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Antiparasitics
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Used to treat scabies and pediculosis. Crotamiton (Eurax) Ivermectin Lindane Malathion (Ovide) Permethrin (Elimite, Nix, Acticin)
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Stimulants and Irritants
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Produce mild irritation of the surface of the skin, causing hyeremia and inflammation, which promote the healing process. Benzion compund Coal tar-Tx of psoriasis, seborrheic dermatitis, and atopic dermatitis. may cause phototoxicity
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Enzymes
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Used to promote healing wounds and to debride necrotic tissue and skin ulcers. Collagenase (Santyl):* apply only to injured areas, causes erythema in healthy tissues, protect healthy tissues by applying zinc oxide paste. Dextranomer (Debrisan):*not debriding agent but cleansing agent that absorbs peptides and protiens. Fibrinolysin and desoxyribonuclease (Elase): *used mostly for burns and pressure ulcers Sutilains (Travase):*used mostly for burns
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Acne Products
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Topical anti-inflammatory medications. Tretinoin (Retin-A) *decreases the cohesiveness of the epithelial cells, thereby increasing cell mitosis and turnover Isotretinoin (Accutane) *tx of severe cystic acne. Avoid alcohol consumption, may potentiate serum triglyceride elevation.
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Poison Ivy Treatment
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Bentoquatam (for preventive use; Ivy Block) Calamine Lotion (Caladryl Lotion) Hydrocortisone (Ivy Soothe; Ivy Stat) Isopropanol, cetyl alcohol (Ivy Cleanse) Zinc acetate, isopropanol (Ivy Dry) Zinc acetate, isopropanol, benzyl alcohol (Ivy Super Dry)
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Burn Products
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Nitrofurazone (Furacin): Used in burns when bacterial resistance to other agents is a problem Mafenide aceate (Sulfamylon): Tx of burns to reduce bacteria present in avascular tissues Silver sulfadiazine (Silvadene): used primarily to prevent sepsis among clients with burns. Silver Nitrate: apply to dressing not on wound. an antiseptic solution that is active against gram-negative bacteria.