Chapter 16

25 July 2022
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Which of the following is NOT a part of external respiration
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the use of oxygen and generation of CO2 by the Mitochondria during energy metabolism
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which of the following specifically describes the movement of air into and out of the lungs?
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pulmonary ventilation
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which of the following is not a function of the respiratory system?
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acid-base balance of blood
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which the primary anatomical difference that marks the dividing line between the conducting zone and the respiratory zone of the respiratory tract?
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the thickness of the walls surrounding the air spaces
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what is the significance of the respiratory membrane to facilitate gas exchange?
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Epithelial and endothelial cells share acommon basement membrane
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why are alveoli arranged in small grape-like clusters?
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maximize surface area and minimize thickness
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what are the smallest (and most distal) structures that remain a component of the conducting zone in the respiratory tract?
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terminal bronchioles
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what is the function of ciliated cells in the conducting zone?
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propel mucus containing trapped particles toward the glottis
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which of the following becomes more abundant deeper into the conducting zone (from bronchi to bronchioles)?
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smooth muscle
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which of the following is most abundant in the trachea and bronchi, becoming much less dense (and eventually absent) in the bronchioles?
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cartilage
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the transition from the conducting to the respiratory zone in the lungs occurs at the
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respiratory bronchioles
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what is the function of alveolar pores?
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equalize pressure in the lungs
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what are the most common cells that line the surface of the alveoli and are therefore associated with the exchange of gases within the lungs?
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type I alveolar cells
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what is the thin barrier (0.2um) that allows for the efficient exchange of gases between the lungs and the blood called?
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respiratory membrane
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what happens to a dust particle that is too large to stay airborne and land in the alveoli?
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it lands in the mucociliary ladder and moves to the pharynx to be swallowed
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what happens to a dust particle that is too small to fall from the inspired air and land in the alveoli?
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it is inhaled and then exhaled
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mycoplasma tuberculosis, the causative agent in tuberculosis, primarily infects the alveolar macrophages and is therefore very fortunate in its size. Why is this statement true?
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it is too small to be caught in the mucociliary ladder and too large to be immediately exhaled, thereby landing it in the alveoli.
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an ex-smoker with emphysema has a pulmonary erosion into his intrapleural space. What life-threatening condition is he at imminent risk of developing?
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pneumothorax (air leaking into the intrapleural space)
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what keeps the visceral pleura in close proximity to the parietal pleura?
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surface tension of the intrapleural fluid
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the COPD called emphysema forces the afflicted to exhale through pursed lips to maintain intrabronchial back pressure, thereby preventing
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airway collapse
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which of the following is a chronic inflammatory pulmonary disorder characterized by reversible obstuction of the airways?
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asthma
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when air is no longer moving through the respiratory tract and the airway is open to the environment, the pressure within the lung is equal to?
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atmospheric pressure
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the difference between what two pressures drives air into and out of the lungs?
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atmospheric and intra-alveolar
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which of the following occurs when intra-alveolar pressure exceeds atmospheric pressure
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air moves out of the lungs
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which of the following varies rhythmically with respiration
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both intrapleural pressure and intra-alveolar pressure
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the difference between intrapleural pressure and intra-alveolar pressure is
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transpulmonary pressure
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which of the following is a measure of the distending force across the lungs?
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transpulmonary pressure
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equilibration of pressure between the intrapluural space and the alveoli will lead to which of the following?
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a pneumothorax (the lung will collapse)
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what is the vol. of air present in the lungs when the lungs are at rest (in between breaths)?
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functional residual capacity
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which of the following is TRUE when the lung volume is equal to the functional resifual capacity?
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the elastic recoil of the lungs is balanced by the elastic recoil of the chest wall
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as the lungs expand, intra-alveolar pressure _______ and air moves _______ the lungs.
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decrease: into
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as the volume of the lung increases, atmospheric pressure
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will not change
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what does contraction of the diaphragm cause?
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increase in the colume of the thoracic cavity and, therefore, a decrease in intra-alveolar pressure
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what are the primary inspiratory muscles?
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diaphragm and external intercostals
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the muscles of respiration are
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skeletal muscle, innervated by the somatic nervous system
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as volume of the chest wall increases, the concomitant expansion of the lungs is due to a(n)?
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increase in transpullmonary pressure
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at rest, expiration it a(n) _______ process that involves _______.
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passive : relaxation of the diaphragm and external intercostals
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which of the following pressures is lower during inspiration then during expiration?
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both intra-alveolar and intrapleural pressures
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the compliance of the lungs can be determined by measuring the change in ____ for a given change in _____.
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lung volume; transpulmonary pressure
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the compliance of the lung is determined by the elasticity of the lung and
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surface tension
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the surface tension of the alveolus is reduced by surfactants produced by what type of cells?
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type II alveolar
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which of the following is NOT involved in altering the resistance of the airway to air movement?
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pulmonary surfactant concentration
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how do tractive forces affect the airways during inspiration?
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decrease in airway resistance
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which of the following is respndible for changes in airway resistance that occur in a single breath?
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passive forces exerted on the airways
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which of the following chemicals will NOT result in a decrease in airway resistance?
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histamine
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which of the following is NOT part of the response of an airway to specific allergens that initiate an asthmatic response?
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increased relese of corticosteroids
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what benefit are corticosteroids in the treatment of asthma?
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they reduce inflammation of the airways
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A(n) _____ is used clinically to measure lung volumes and rates of air flow.
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spirometer
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what is the volume of air moved into and out of the lungs in a single breath during unforced breathing called?
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tidal volume
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the presence of a negative intrapleural pressure at maximum expiration is responsible for which of the following?
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residual volume
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the tidal volume and inspiratory reserve volume together make up which of the following?
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inspiratory capacity
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functional residual capacity is comprised of which of the following
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residual volume and expiratory reserve volume only
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which of the following measurements cannot be determined by a spirometer?
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residual volume
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a normal tidal volume at rest is approximately _____ mL.
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500
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a normal vital capacity is approximately ___mL.
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4500
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a healthy person can normally exhale what percentage of his or her vital capacity in one second?
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80
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in an obstructive disease, the lungs can become overinflated because the difficulty in _____ tends to ______.
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expiration: increase residual volume and total lung capacity
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a decrease in _____ is indicative of a restrictive pulmonary disease
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vital capacity
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a decrease IN _________ is indicative of an obstructive pulmonary disease.
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forced expiratory volume
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what is the term for the volume of air moved into the lungs every minute?
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minute ventilation
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what is the term for the volume of air that reaches the respiratory zone each minute?
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alveolar ventilation
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what is the volume of the respiratory pathway that is NOT able to exchange hases (conducting pathway) called?
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anatomical dead space
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what happens to the inner diameter of the walls of the respiratory tract as it moves down from the upper conducting zone to the lower respiratory zone?
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decrease
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what happens to the amount of cartilage in the walls of the respiratory tract as it moves down from the upper conducting zone to the lower respiratory zone?
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decreases
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what happens to the amount of cilia lining the inner walls of the respiratory tract as it moves down from the upper conducting zone to the lower respiratory zone?
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decreases
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what happens to the number of goblet cells found in the walls of the respiratory tract as it moves down from the upper conducting zone to the lower respiratory zone?
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decreases
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what happens to the amount of smooth muscle found in the walls of the respiratory tract as it moves down from the upper conducting zone to the lower respiratory zone?
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decreases
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which cells secrete surfactant?
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type II alveolar cells
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which cells secrete mucus
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goblet cells
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which cells form the mucus escalator?
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ciliated cells
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which cells engulf foreign particles that reach the lungs
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alveolar macrophages
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which cells form the lung tissue component of the respiratory membrane?
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type I alveolar cells
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which pressure is created by the elastic recoil of the lungs and chest wall?
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intrapleural pressure
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which pressure is constant during the respiratory cycle?
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atmospheric pressure
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which pressure is the distending force on the lungs?
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transpulmonary pressure
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which of the following has the difference between its pressure and atmospheric pressure driving the air into and out of the lungs?
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intra-alveolar pressure
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which pressure equals atmospheric pressure during a pneumothorax, causing the lungs to collapse?
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intrapleural pressure
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which pressure changes with the phases of respiration but is always negative?
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intrapleural pressure
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which pressure changes with the phases of respiration from a negative value during inspiration and a positive value during expiration?
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intra-alveolar pressure
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the volume of air remaining in the lungs following a maximum expiration is called
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residual volume
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the volume of air exchange with the environment during an unforced breath is called?
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tidal volume
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the maximum volume of air that can be inspired following a resting inspiration is called
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inspiratory reserve volume
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the maximum volume of air that can be inspired following a resting expiration is called
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inspiratory capacity
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the maximum volume of air that can be expired following a maximum inspiration is called
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vital capacity
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the maximum volume of air that can be expired following a resting expiration is called
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expiratory reserve volume
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the volume of air in the lungs following a maximum inspiration is called
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total lung capacity
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the volume of air in the lungs at rest, between breaths, is called?
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functional residual capacity
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tidal volume + inspiratory reserve volume is called
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inspiratory capacity
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what is the residual volume + expiratory reserve volume called?
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function residual capacity
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what is the tidal volume + Inspiratory reserve volume + expiratory reserve volume called?
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vital capacity
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what is the tidal volume + inspiratory reserve volume + expiratory reserve volume + residual volume called?
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total lung capacity
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what is the primary determinant of airway resistance?
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airway radius
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the intra-alveolar pressure is determined by what two factors?
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quantity of air in the alveolus and volume of the alveoli