Behavioral Neuroscience Final

25 July 2022
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question
Autoreceptors are located on the ________ and detect ________
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presynaptic membrane; the transmitter released by that neuron
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Which of the following is correct regarding axoplasmic transport? a. Dendrograde transport involves moving substances from the dendrites to the soma b. Retrograde transport involves moving substances from the soma to the axon terminals c. The kinesin molecule is involved in anterograde transport d. Retrograde transport is twice as fast as anterograde transport e. The dynein molecule is involved in anterograde transport
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c. The kinesin molecule is involved in anterograde transport
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With regard to release of neurotransmitter in the brain, "kiss and run" refers to the situation in which the vesicle
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releases most of its contents into the cleft, after which the vesicle breaks away from the presynaptic membrane and is refilled
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Neurotransmitter release from the presynaptic membrane is triggered by the
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influx of calcium ions into the axon terminal
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Synapses are most commonly formed between a (n) ________ and a(n) ________
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terminal button; dendrite
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Myelination of brain nerve axon membranes is accomplished by ________ cells
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oligodendrocyte
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In terms of the Blood-Brain Barrier, activation of cells within the ________ by a poison in the blood would be predicted to produce ________
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area postrema; vomiting
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Which of the following is consistent with the "all-or-none law"? a. The action potential will diminish to near 0 mV when transmitted down a long axon b. The action potential fires at the same rate regardless of the inputs to the neuron c. The action potential is conducted more rapidly down the axon as it reaches the axon terminal d. The action potential is produced whenever the membrane potential reaches threshold e. The action potential travels only in one direction
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d. The action potential is produced whenever the membrane potential reaches threshold
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The most common neuron type in the central nervous system is the ________ neuron
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multipolar
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An EPSP will be produced when a ligand a. opens a sodium channel b. closes a sodium channel c. opens a potassium channel d. closes a calcium channel e. closes a chloride channel
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a. opens a sodium channel
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The ________ mediates the inflammatory reaction that follows brain damage
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microglia
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Which of the following is an important advantage associated with saltatory conduction? a. More sodium ions have to be pumped out of the cell after an action potential b. Myelin allows the nerve cell to recycle neurotransmitter molecules c. Less transmitter is required to send a message across the next synapse d. Myelin speeds up the velocity at which an axon can conduct an action potential e. Myelin requires that nerve cell axons be larger in order to conduct a signal rapidly
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d. Myelin speeds up the velocity at which an axon can conduct an action potential
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Which of the following is true of ion distribution across the axon membrane? a. Chloride ions are concentrated inside the axon membrane b. Potassium ions are concentrated inside the cell nucleus c. The action potential is the balance point between diffusion and electrostatic pressure d. Sodium ions are concentrated outside the axon membrane e. Sodium ions are concentrated inside the axon membrane
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d. Sodium ions are concentrated outside the axon membrane
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The interior of a neuron at rest
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is negatively charged relative to the outside
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Among the cable properties of axons are the fact that
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subthreshold signals degrade with distance from the point of stimulation
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Match up the correct receptor type and effect. a. metabotropic; direct opening of an ion channel b. ionotropic; more time required to open an ion channel c. metabotropic; G protein activation leads to activation of a second-messenger d. metabotropic; rapid opening of a single ion channel e. metabotropic; rapid short-lived effects on ion channels
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c. metabotropic; G protein activation leads to activation of a second-messenger
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Which of the following represents a correct match between a neuronal organelle and its function? a. mitochondria; extraction of energy b. Golgi apparatus; extraction of energy c. endoplasmic reticulum; breakdown of proteins d. microtubules; transport of chemicals through the cell membrane e. mitochondria; formation of vesicles
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a. mitochondria; extraction of energy
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Which of the following is NOT a function of the glial cells? Select one: a. provision of nutrition to the brain b. removal of physical debris from the brain c. physical support of neurons d. insulation of nerve cells from each other e. the conduction of action potentials
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e. the conduction of action potentials
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The postsynaptic potentials induced by most neurotransmitters are ended by a. disruption of the postsynaptic receptor b. enzymatic degradation of the transmitter molecule c. inhibition of transmitter synthesis d. facilitation of transmitter release e. reuptake of the molecule into the axon terminal
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e. reuptake of the molecule into the axon terminal
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The ________ is the voltage level at which an action potential is triggered in a patch of axon membrane.
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Threshold of excitation
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Communication of neural signals across the synapse involves a. the opening of voltage-gated channels in the axon terminal b. voltage changes that open calcium channels in the presynaptic membrane c. vesicles that release transmitter molecules into the synapse d. the binding of transmitter at postsynaptic receptors triggering membrane potentials e. All are correct
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e. All are correct
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A change in the axon membrane potential from -70 mV to -90 mV would be termed a(n) a. depolarization b. threshold potential c. action potential d. hyperpolarization e. excitatory local potential
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d. hyperpolarization
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The ________ is that portion of the nervous system that lies outside of the brain and spinal cord.
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peripheral nervous system
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Surplus substances within the cytoplasm are broken down by a. mitochondria b. ribosomes c. lysosomes d. the cytoskeleton e. A and C are correct
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c. lysosomes
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A key function of the _______ nerve cell is to transmit sensory information a. apolar b. multipolar c. unipolar d. bipolar e. both C and D are correct
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e. both C and D are correct
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Which type of Alice in Wonderland Syndrome is the most prevalent?
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Type B
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What is the cause of Alice in Wonderland Syndrome?
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The cause has not yet been confirmed
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The neurological disorder "Alice in Wonderland Syndrome" inspired Lewis Carroll to write his famous novel (T or F)
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False- it was thought Lewis Carroll had the syndrome himself
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What is another name for Cotard's Syndrome?
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Walking Corpse Syndrome
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Capgras Syndrome is more common in who?
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Women
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Upon researching patients admitted into a psych unit for Capers Syndrome, how many cases of Schizophrenia were found?
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50%
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Which part of the brain suffers a bilateral lesion in Kluver-Bucy Syndrome?
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Amygdala
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Symptoms of Kluver-Bucy Syndrome
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loss of appetite, emotional changes, memory loss
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What disorders are related to Kluver-Bucy Syndrome?
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Alzheimer's and Korsakoff Syndrome
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Percentage of population with Congenital Amusia
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4%
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Most common type of synesthesia
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Grapheme-color
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People with Lexical-gustatory synesthesia experience
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ability to taste words/numbers
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Synesthesia can occur bidirectionally (T or F)
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True
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Umbrella term is classify delusion disorders (ex Fregoli Syndrome)
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DMS
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This disease is linked to development of Fregoli Syndrome
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Huntington's Disease
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Treatment options for patients with Fregoli Syndrome
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Antidepressants, anticonvulsants, antipsychotics
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Causes of Anton-Babinski Syndrome
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Cerebrovascular disease, damage to occipital lobe, trauma from stroke
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Anton-Babinski Syndrome is a type of
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Anosognosia
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Someone who is unaware of their blindness might have
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Visual anosognosia or Anton-Babinski Syndrome
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Acquired amnesia is caused from brain damage (T or F)
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True
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Which of the following do NOT belong together? a. occipital lobe; visual function b. frontal lobe; motor function c. frontal lobe; auditory function d. insular cortex; taste function e. temporal lobe; auditory function
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b. frontal lobe; auditory function
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In which view of the brain would one be able to note the presence of a specific structure in both hemispheres at the same time?
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frontal
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The myelencephalon contains one major structure, the ________ , which is the most caudal portion of the brain stem
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medulla oblongata
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The structures that comprise the basal ganglia include the
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putamen, globus pallidus, caudate nucleus
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The midbrain is comprised of the
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tectum and tegmentum
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Dopamine receptors are metabotropic (T or F)
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True
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On the 28th day of embryonic development, the human brain resembles a
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Hollow tube
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Which of the following is NOT correct regarding CSF? a. CSF is produced by the choroid plexus b. The total brain volume of CSF is about 125 ml c. CSF functions to cushion the brain against sharp movements d. Less than 2 hours is required to replace the total CSF volume in a human brain e. Loss of CSF would result in compression of brain tissue onto the ventral skull surface
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d. Less than 2 hours is required to replace the total CSF volume in a human brain
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CSF is produced within the ________ and reabsorbed into the blood by the ________
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ventricles; arachnoid granulations
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A ________ refers to a bulge of tissue located between the adjacent grooves in the surface of the human cortex
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fissure
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Axons that travel within the ________ connect the hippocampus to the mammillary bodies
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fornix
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The two most commonly used synaptic neurotransmitters in the brain are
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glutamate; GABA
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The term "neuraxis" refers to
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an imaginary line drawn through the spinal cord up to the front of the brain
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Which of the following represents the correct pairing of a thalamic nucleus with its projection to cortex? a. medial geniculate nucleus; projects to primary visual cortex b. ventrolateral nucleus; projects to primary visual cortex c. lateral geniculate nucleus; projects to primary visual cortex d. ventrolateral nucleus; projects to primary somatosensory cortex e. lateral geniculate nucleus; projects to primary motor cortex
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c. lateral geniculate nucleus; projects to primary visual cortex
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A ________ section is made through the human brain and is parallel to the ground, and a ________ section through the spinal cord is parallel to the ground
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horizontal; transverse
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The metencephalon is comprised of the
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pons and cerebellum
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Neurons within the cortex are arranged in columns in part because
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cells within the column travelled along the same radial glial fiber
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Damage to portions of the limbic cortex would be expected to alter
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emotion, the ability to recognize emotion in others, long-term memory, the ability to learn and retain new information
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Match up the transmitter substance below with the appropriate behavioral role or action of that transmitter: a. acetylcholine; muscular movement b. dopamine; suppresses certain species-typical behaviors c. norepinephrine; facilitation of learning d. serotonin; increases vigilance e. GABA; generally activates voluntary movements
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a. acetylcholine; muscular movement
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The brain floats within ________ fluid, which is contained within the ________
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cerebrospinal; subarachnoid space
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The ______ is a tough protective sheath that covers the brain and lies closest to the skull
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dura mater
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The ________ region of cortex lies buried within a fissure between the ________ and the ________ lobes
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insular; frontal; temporal
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A key function of apoptosis is
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terminate the formation of new neurons within the developing brain.
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Which of the pairs belong together? a. epinephrine and adrenaline b. nicotine and glycine c. noradrenaline and norepinephrine d. serotonin and drug abuse e. A and C are correct
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e. A and C are correct
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Which of the following would be expected following damage to cortex that lies just in front of the central sulcus? a. intense hypersexuality b. visual hallucinations c. inability to discriminate tones as low intensities d. difficulty in reading and writing e. difficulty in controlling the muscles of the body
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e. difficulty in controlling the muscles of the body
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________ will occur soon after the appearance of rapid eye movements in the sleep record
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Paradoxical sleep
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An electro-oculogram is an instrument used in sleep studies to measure
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eye movements
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Which of the following is true of melanopsin? a. Melanopsin is found within rods but not cones b. Melanopsin is found within cones but not rods c. Melanopsin activity is suppressed by light d. Melanopsin is found within ganglion cells e. Melanopsin in rods is a cue that resets SCN clock cells
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d. Melanopsin is found within ganglion cells
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Arousal is promoted by these neurotransmitters
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histamine, norepinephrine, acetylcholine, serotonin
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Upon waking, a person who is immobilized but remains conscious may be suffering from
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sleep paralysis
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Which of the following are true of neurons within the ventrolateral preoptic area (vlPOA)? a. Damage to vlPOA neuron produces sleepiness b. Excitotoxic lesions of the vlPOA increased sleep in cats c. vlPOA neurons have a low firing rate during sleep d. Electrical stimulation of vlPOA neurons produces signs of drowsiness e. vlPOA neurons secrete glutamate to excite regions that control arousal
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d. Electrical stimulation of vlPOA neurons produces signs of drowsiness
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A genetic mutation of the hypocretin gene in mice results in
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symptoms of narcolepsy
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Which of the following is true of human sleep cycles? a. Sleep cycles are random across the night b. Subjects first enter REM sleep and then transition to non-REM sleep c. As the night goes on, the relative length of REM sleep increases in each successive cycle d. Stages 3 and 4 of slow-wave sleep mostly occur in the early morning hours e. Each non-REM/REM cycle lasts about 45 minutes
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c. As the night goes on, the relative length of REM sleep increases in each successive cycle
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Prolonged sleep deprivation in humans results in
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impaired mental concentration, autonomic dysfunction, some perceptual hallucinations, REM rebound
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Recent research suggests that ______ sleep is important for ______ memory. a. Slow-wave; nondeclarative b. REM; nondeclarative c. REM; declarative d. Slow wave; declarative e. B and D are correct
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e. B and D are correct
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Which of the following treatments would be expected to increase locomotion and to enhance the amount of cortical arousal evident in an EEG record? a. electrical stimulation of the frontal cortex b. damage to the locus coeruleus c. damage to the raphe nuclei d. electrical stimulation of the raphe nuclei e. injection of high levels of GABA into the raphe nuclei
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d. electrical stimulation of the raphe nuclei
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Circadian rhythms are
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endogenous cycles of activity over the course of a day
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Caffeine promotes wakefulness because it is a(n)
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adenosine antagonist
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A ________ is a stimulus that resets an internal biological clock
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zeitgeber
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Somnambulism is synonymous with
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sleepwalking
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You are watching the sleep record of a person whose record contains 85% delta wave activity. Your best guess is that this person is
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in stage 4 of slow-wave sleep
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A key source of noradrenergic neurons in the brain is the
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locus coeruleus
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REM-ON neurons are located within the _______, whereas REM-OFF neurons are located within the _______
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sublateral dorsal nucleus; ventrolateral PAG
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Deprivation of REM sleep on one night results in an elevated amount of REM sleep on the following night. This rebound phenomenon suggests that
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there is a physiological need for a certain amount of REM sleep
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________ refers to the vivid visions that may occur during sleep paralysis
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Hypnagogic hallucination
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Which of the following is true of sleeping medications? a. Sleeping pills can lead to more severe insomnia b. Sleeping pills directly alter the cause of insomnia c. Insomnia is a disease that can be cured by a pill d. Unlike other drugs, persistent use of sleeping pills does not lead to tolerance e. B and D are correct
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a. Sleeping pills can lead to more severe insomnia
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A key symptom of REM-sleep behavior disorder is
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a lack of paralysis during REM sleep
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A buildup of carbon dioxide in the blood is a characteristic of ________
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sleep apnea
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The capacity of circuits involving the vlPOA and the locus coeruleus, raphe nuclei, and dorsal pons to show mutual inhibition may result in
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the alternation between sleep and waking
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The metabolism of glycogen within astrocytes produces ________, which in turn promotes ________
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adenosine; slow-wave sleep
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Functional imaging studies of the brain during decision-making suggest that personal moral dilemmas strongly activate the
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ventromedial prefrontal cortex
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The emotion of disgust involves activation of neurons within the
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insular cortex
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The autonomic component of an emotional response functions to
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mobilize energy for vigorous movement
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Research suggests that serotonin exerts a controlling effect on
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risky behaviors
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A human male who has a long record of assault, arson, and murder would be expected to show ________ levels of ________ in his cerebrospinal fluid
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reduced; 5-HIAA
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The muscular movements that are involved in laughter are controlled by neurons within the
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anterior cingulate cortex
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A species-typical defensive response for a rat would include
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freezing of motor movements
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With regard to facial emotional expression,
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negative emotional expressions are more intensely expressed on the left side of the face
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Which of the following distinguishes predation from most types of aggression? a. Predation is not accompanied by sympathetic activation in the predator b. The object of predatory attack experiences more sympathetic activation than that seen when two members of the same species engage in aggression c. A predator is highly likely to terminate the attack when the prey shows submissive behaviors d. engage in aggression e. None of these answers are correct.
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a. Predation is not accompanied by sympathetic activation in the predator
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fMRI and macro-electrode studies suggest the _____ receives information from the _______, which permits it to recognize facial expressions of fear
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amygdala; magnocellular system
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The amygdala is involved in the recognition of ________ communicated via ________
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fear; facial expression
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The expression of emotional responses is inhibited by inputs from the
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ventromedial prefrontal cortex
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The ability to recognize emotions expressed by others is most likely to be impaired after damage to the
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right hemisphere
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Mice lacking the 5-HT1B receptor show ________, thus supporting the proposition that ________
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increased aggression; serotonin inhibits aggression
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According to the James-Lange theory, feelings of emotions are
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produced by feedback from the behaviors and physiological responses caused by emotion producing situations
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An intact ________ is required in order for a conditioned emotional response to alter blood pressure
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lateral hypothalamus
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Phineas Gage, who was injured when a steel rod was accidentally driven through his skull, exhibited capricious, emotional behavior (in part) as a result of widespread damage to his
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ventromedial prefrontal cortex
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______ is an example of a personal moral dilemma
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Physically throwing another person onto a grenade to save everyone else in the area
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The major components of an emotional response include
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behavior, autonomic activity, and hormonal secretions
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Inactivation of the central nucleus results in
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reduced blood levels of stress hormones
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Which of the following supports the contention that the central nucleus of the amygdala (CN) integrates emotional responses? a. Destruction of the CN reduces emotional responses b. Electrical stimulation of the CN produces fear and anxiety c. Conditioned emotional responses are not learned by rats sustaining CN damage d. The CN sends projects to brain regions than in turn control autonomic and behavioral emotional components e. All of the above are correct
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e. All of the above are correct
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The amygdala is involved in ________, but not in ________
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recognition of facial expression; Moebius syndrome
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The proposition that facial expressions of emotion are innate is supported by the observation that
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the same facial expression for an emotion is observed in all cultures
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People with volitional facial paresis are unable to
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voluntarily move the facial muscles
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Electrical stimulation of the ventral periaqueductal gray matter in the cat produces
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predatory behavior
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The most profound symptom of Korsakoff's syndrome is
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anterograde amnesia
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The ______ hippocampal formation is activated by _______
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right; spatial information
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The key function of instrumental conditioning is to allow the organism to
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adjust behavior according to its consequences
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People with retrograde amnesia cannot
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recall events that occurred prior to the brain injury
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The NMDA receptor controls ________ and is normally blocked by ________
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a calcium channel; magnesium ions
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You are listening to a song on the radio while doing your homework. The phone rings. Your mother has called to tell you that your favorite uncle has died after being hit by a car. Three months later, you again hear the same song and suddenly feel very sad. In this example, the unconditional response is
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feeling sad when your mother calls with the bad news
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Studies by Schultz and colleagues suggest that release of dopamine within the nucleus accumbens
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is greatest for an unexpected reinforcing stimulus
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The NMDA receptor is unusual in that it is ________ -dependent and ________ -dependent
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voltage; neurotransmitter
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The ventral stream of visual association cortex continues into the ________ and carries information relating to ________
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inferior temporal cortex; object recognition
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An example of a task that measures perceptual learning would be
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recognizing broken drawings
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In a conditioned emotional response (CER) study, a tone is paired with a foot shock for a rat. After several trials, the tone alone is a CS that can elicit fear emotional responses. Which of the following is true of the physiology of this fear response? a. Damage to the lateral nucleus of the amygdala impairs CER learning b. Tone-shock pairings rapidly decrease the electrical activity of the lateral nucleus of the amygdala c. Damage to the basal ganglia impairs CER learning d. Inactivation of the ventral nucleus of the amygdala during CER training blocked the formation of the CER e. Damage to the amygdala facilitates emotional responding
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a. Damage to the lateral nucleus of the amygdala impairs CER learning
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the process by which immediate memories are transformed into long-term memories
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consolidation
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In which of the following would you expect to observe an enlarged hippocampal formation? a. a London cab driver who has 30 years of experience b. a pigeon that wanders from roost to roost c. a bird that only eats from your back yard feeder d. a person who has just started training as a London cab driver e. a chickadee tested in the early summer
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a. a London cab driver who has 30 years of experience
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The distinction between implicit and explicit memories is that
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we are unable to talk about implicit memories
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Based on the study of Patient H.M., it has been concluded that
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the hippocampus converts short-term memories into long-term memories
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The perforant pathway
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interconnects the entorhinal cortex with the granule cells of the dentate gyrus.
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Which of the following terms are synonymous? a. nondeclarative memory; explicit memory b. declarative memory; explicit memory c. short-term memory; long-term memory d. declarative memory; implicit memory e. Hebbian memory; consolidation
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b. declarative memory; explicit memory
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A person with semantic dementia would be expected to show
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difficulty in recalling factual information
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Which of the following is important for the acquisition of complex behaviors? a. As a person becomes proficient in the behavior, the control of the process is transferred to the basal ganglia b. As a person becomes proficient in the behavior, the control of the process is transferred to the transcortical pathways c. The behavior must result in long-term depression in the basal ganglia d. The behavior must result in long-term depression in the motor cortex e. As a person becomes proficient in the new behavior, the transcortical circuits become more depressed
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a. As a person becomes proficient in the behavior, the control of the process is transferred to the basal ganglia
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The ________ states that a weak synapse will be strengthened if its activation occurs at the same time that the postsynaptic neuron fires
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Hebb Rule
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The induction of LTP in the hippocampus would be blocked by
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a drug such as AP5 that blocks NMDA receptors
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Associative long-term potentiation (LTP) requires ________ occur about the same time as _______
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activation of a strong input to a given synapse to; a weak input is activated
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An action potential that occurs in a dendritic spine is termed
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the dendritic spike
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An example of relational learning is a. recognizing a familiar stimulus b. salivating in response to a favorite food c. forming a mental map of a room based on your experience in the room d. practicing a golf swing repeatedly results in more accurate strokes e. failing to respond to a loud sound given repeatedly
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c. forming a mental map of a room based on your experience in the room
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Your ability to recognize a series of tones, such as the opening notes of "The Star Spangled Banner" is an instance of ________ that likely involves the ________
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perceptual learning; auditory association cortex
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A genetic disorder caused by a mutation that fails to produces a protein that is required for normal health would be classified as
answer
toxic loss of function
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The cause of neuron cell death after a stroke usually involves
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overstimulation of nerve cells by abnormally high synaptic levels of glutamate
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Rabies is a type of
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viral encephalitis
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A person who has a series of seizures without regaining consciousness would be classified as having
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status epilepticus
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An aura involving the recall of a childhood memory would most likely reflect seizure activity within the
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temporal lobes
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A key sign that a child born to a mother who consumed alcohol during the pregnancy suffers from fetal alcohol syndrome involves
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abnormal facial development
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The cause of Parkinson's disease has been traced to
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degeneration of dopamine neurons within the nigrostriatal system
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Which of the following is a hereditary disorder that causes degeneration of GABA secreting neurons in the putamen of the basal ganglia? a. Huntington's disease b. Tay-Sachs disease c. Meissner's syndrome d. Down syndrome e. Parkinson's disease
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a. Huntington's disease
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Phenylketonuria is caused by
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an inherited lack of an enzyme that produces tyrosine.
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Failure to diagnose and treat pyridoxine dependency or galactosemia can result in damage to the
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cerebral white matter
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A key distinction is that Parkinson's disease ________ , whereas Huntington's chorea _______
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is characterized by a poverty of movement; is characterized by uncontrollable ones
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A(n) ________ is an example of a malignant tumor derived from glial cells
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oligodendrocytoma
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Malignant brain tumors are deadly because such tumors a. can block the flow of cerebrospinal fluid thus causing hydrocephalus b. compress adjacent brain cells c. give off cells that travel to other body areas and result in new tumors d. are difficult to completely remove from brain tissue e. All of the above are correct
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e. All of the above are correct
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Meningitis leads to damage of the brain because this disease produces
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inflammation of the meninges that interferes with the flow of blood or cerebrospinal fluid
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A major cause of obstructive strokes is
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a thrombus or an embolus
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Prolonged interruption of the blood supply to a region of the brain results in
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ischemia
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In contrast to simple partial seizures, complex partial seizures involve
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loss of consciousness
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A genetic disorder caused by a mutation that produces a protein with toxic consequences would be classified as
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toxic gain of function
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Surgical removal of the ________ can alleviate the symptoms of Parkinson's disease
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globus pallidus
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The key characteristic of a benign tumor is that such a tumor
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has a distinct border
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During the ________ of a grand mal seizure, the person experiences a(n) ________
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tonic phase; contraction of all skeletal muscles
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Seizures that are caused by alcohol withdrawal involve changes in ______ signaling in the brain
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NMDA
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A therapy for Parkinson's disease that alters MAO-B activity in nerve cells involves
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administration of deprenyl
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A child that has Tay-Sachs disease would be expected to show
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exaggerated startle responses, listlessness, and irritability
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An autoimmune reaction that damages ________ is the cause of the multiple sclerosis
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the myelin sheaths surrounding nerve cells
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Someone with aprosodia cannot identify another's emotion based on facial expressions (T or F)
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False
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Parts of the brain injured in aprosodia
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left hemisphere, right hemisphere (most common), subcortical region
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Over the phone, Bobby couldn't tell that his mom as angry when she told him to clean his room. What kind of aprosodia is this?
answer
Affective
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People with Charles Bonnet Syndrome only have "simple" hallucinations (T or F)
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False
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Why do people not report their hallucinations to doctors?
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They think people will think they are crazy
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The psychological side effects of Charles Bonnet Syndrome can be treated with medications (T or F)
answer
True
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In Alien Hand Syndrome, researchers use what techniques to measure AHS?
answer
Somatosensory evoked potential (SEP) and transcranial magnetic stimulation (TMS)
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In Alien Hand Syndrome, the right hand struggles to form a pattern while the left (alien) hand solves it easily (T or F)
answer
True
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Split brain patients
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โ€ขleft hemisphere (controls right side of body) works, right hemisphere (controls left side of body) does not