Chapter 19

24 July 2022
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question
In which process can glucose transport reach saturation?
answer
reabsorption
question
The kidneys function to produce hormones, excrete wastes, regulate blood pressure, and maintain ion balance. Which of the following is another function of the kidneys?
answer
Regulate osmolarity
question
Approximately how much liquid moves through the kidneys of an adult during a 24-hour period?
answer
180 liters
question
Approximately what percent of the total filtered volume is excreted as urine each day?
answer
less than 1%
question
When the plasma concentration of a substance exceeds its renal concentration, more of the substance will be
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excreted
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Match each step in urine formation to its description. A. excretion B. filtration C. reabsorption D. secretion movement from the peritubular capillaries to the nephron lumen
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secretion
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Urine is produced by the
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kidney
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Put the following in order from where urine is produced to where it exits the body: 1.Urethra 2.Urinary bladder 3.Nephron 4.Ureter
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3,4,2,1
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A patient has a genetic defect that decreases the number of GLUT transporters in the nephron tubule. Which would you expect?
answer
Decreased transport maximum and increased glucose in urine
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The functional unit of the kidney is the __________.
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nephron
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During the micturition reflex, what does activation of parasympathetic efferent neurons cause the bladder to do?
answer
contract
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Contents in the peritubular capillaries are actively transported into proximal and distal convoluted tubules in a process known as
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secretion
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Which change would cause an increase in afferent arteriolar resistance due to paracrine signaling from the macula densa?
answer
Greater sodium concentration in the distal tubule
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Which is NOT a function of the kidneys?
answer
regulation of blood protein levels
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Match each step in urine formation to its description. A. excretion B. filtration C. reabsorption D. secretion movement from the nephron lumen to the external environment
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excretion
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Most reabsorption of fluid from the filtrate back into the blood occurs from the __________.
answer
proximal tubule
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Match each step in urine formation to its description. A. excretion B. filtration C. reabsorption D. secretion movement from the nephron lumen to the blood
answer
reabsorption
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When the macula densa detects an increase in NaCl concentration in the renal filtrate, what happens to the glomerular filtration rate (GFR)?
answer
GFR decreases
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If the osmotic pressure in the glomerular capillaries increased from 28 mmHg to 35 mmHg due to dehydration, would net filtration increase or decrease?
answer
net filtration would decrease
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Filtrate flow through the renal tubule increases when glomerular filtration rate_______
answer
increases
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When filtrate flow through the renal tubule increases, reabsorption of sodium chloride by the tubule______
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decreases
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When filtrate flow through the renal tubule increases, the concentration of sodium chloride remaining in the filtrate_____
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increases
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When filtrate flow through the renal tubule increases, the macula densa responds by______vasoconstrictors.
answer
releasing
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When filtrate flow through the renal tubule increases, the afferent arteriole responds by______
answer
vasoconstricting
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If you know that the renal clearance of substance X is zero, which of the following can you say is true about how the kidney handles X?
answer
X is either not filtered or filtered and completely reabsorbed.
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Using what you know about renal handling of Na+, predict the renal clearance of Na+.
answer
Na+ clearance is less than the GFR
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The correct units for clearance of substance M are:
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mL plasma cleared/min
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Match each step in urine formation to its description. A. excretion B. filtration C. reabsorption D. secretion movement from the glomerulus to the nephron lumen
answer
filtration
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Why is inulin administration an effective way of measuring renal clearance rates?
answer
Inulin is neither secreted nor reabsorbed.
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What happens if reabsorption of a substance increases (and filtration and secretion stay the same)?
answer
Decreased excretion of the substance and an increased amount of the substance in blood
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If all glucose is normally reabsorbed in the proximal tubule of the nephron, why do people with diabetes have glucose in their urine?
answer
The plasma concentration is greater than the renal threshold
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Damage to the renal medulla would interfere first with the functioning of the
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collecting ducts.
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Which of the following substances is not normally found in filtrate?
answer
blood cells and large particles Submit
question
What is the primary driving force (pressure) that produces glomerular filtration?
answer
hydrostatic pressure of blood (blood pressure)
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Which substance would be found in higher concentration if the membrane were damaged?
answer
protein
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If the osmotic pressure in the glomerular capillaries increased from 28 mm Hg to 35 mm Hg, would net filtration increase or decrease?
answer
net filtration would decrease
question
Calculate the net filtration pressure if capillary hydrostatic pressure is 60 mm Hg, capillary osmotic pressure is 25 mm Hg, and capsular hydrostatic pressure is 10 mm Hg.
answer
25 mm Hg
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The primary function of the proximal tubule is
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reabsorption of ions, organic molecules, and water.
question
Where does all filtration take place in the kidneys?
answer
Glomerulus