Working With IACUC

Functions of IACUC

What does IACUC stand for?

Which of the following is a role of AAALAC International?

Which organization is responsible for monitoring institutional compliance with PHS Policy?

Which of the following institutions must follow PHS guidelines for animal research?

Which of the following is helpful to the IACUC when reviewing an animal protocol?

Which of the following statements about using a statistical analysis to justify animal numbers is TRUE?

Which of the following statements concerning selection of species for research is FALSE?

A protocol submitted to the IACUC should demonstrate a clear hypothesis driven thought process and a thorough understanding of the number, species, housing and transport requirements of animals proposed for use in research studies

Which of the following is an example of refinement per the three Rs of Russell and Burch?

Which of the following is NOT an example of reduction per the three Rs of Russell and Burch?

The three Rs of Russell and Burch stand for what?

The Animal Welfare Regulations require the IACUC to do what two things regarding alternatives?

What is a primary mission of the Animal Welfare Information Center (AWIC), a part of USDA?

The Johns Hopkins Center for Alternatives to Animal Testing (CAAT), the Institute for In Vitro Sciences, and the European Center for Validation of Alternative Methods (ECVAM) are primarily interested in what area?

Endpoint criteria describe when it is time to do what?

What is the basis for the pain/distress classification system used by most institutions?

Which activity would place a study in pain category B?

Which of the following is TRUE regarding the Animal Welfare Regulations and duplication of experiments?

Non-USDA regulated species are never required to be placed in a pain/distress category.

Which of the following activities WOULD place an animal in category E?

Which parameter would NOT likely be part of an endpoint policy?

Which of the following activities would EXCLUDE an animal from USDA category D?

Which of the following activities would EXCLUDE an animal from USDA category B?

Which of the following are NOT allowed by USDA?

Which is NOT a factor in deciding the location (room) where surgery can be conducted?

Which of the following would NOT be accepted by an IACUC as the sole justification for performing multiple major survival surgeries?

Which statement concerning survival experimental surgery is FALSE?

Which of the following statements about the postoperative period is FALSE?

Surgery that penetrates and exposes a body cavity or produces substantial physical impairment is described as what kind of surgery?

When does the postoperative period end?

The USDA requires documentation of all postoperative care and retention of records for one year after the death of the animal.

Thermal support is an important aspect of postoperative support

Which observation might indicate pain and thus the need for postoperative analgesia?

A simple rule to prevent excess blood collection in an animal is to collect no more than what percentage of body weight as blood at one time?

Methods for substance administration in rats and mice are outlined in which document?

Which of the statements concerning blood collection in mice and rats is TRUE?

What are some reasons for single housing social animals?

Which types of animals must have access to environmental enrichment, as mandated by the Animal Welfare Regulations?

Reasons to provide environmental enrichment?

Environmental enrichment should be applied consistently to all animals that are part of a study

Which of the following statements regarding the use of restraint on animals in a research study is FALSE?

Restraint for brief periods of time during experimental procedures do not need to be mentioned in the animal use protocol

Which of statement is true about the euthanasia of neonatal mice?

Adjunctive methods of euthanasia, such as pithing frogs, should only be performed on animals that are already unconscious.

Methods of euthanasia deemed "acceptable with conditions" may require scientific justification before IACUC approval.

Who is generally given institutional responsibility for deciding if an individual researcher is properly trained to perform animal procedures, as required by law?

Recombinant DNA inserted into the genome of transgenic mice may NOT be covered by the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules

An agent that has high individual risk but low community risk would be in which Risk Group per the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules?

What document provides the guidelines for working with infectious diseases in animal research?

Enrollment in the institutional Occupational Health and Safety program is mandatory before working with animals

The principal investigator is responsible for ensuring all staff are trained to:

Which of the following protocol changes require IACUC approval?

Some types of changes to an animal protocol can be approved administratively by veterinary verification and consultation.

All significant changes to an animal use protocol need to be approved by the IACUC

Protection for those who report misuse of animals or noncompliance is mandated by the Animal Welfare Regulations