Exam 2 Chapter 17

25 July 2022
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question
RNA molecules that do not encode polypeptides are called ...... - ....... RNAs.
answer
non coding
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In this image, an ncRNA is shown bound to what type of molecule?
Multiple choice question.
mRNA
Protein
DNA
Small molecule
In this image, an ncRNA is shown bound to what type of molecule? Multiple choice question. mRNA Protein DNA Small molecule
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mRNA
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Match each ncRNA function to its correct description Scaffold
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Some ncRNAs contain binding sites for multiple molecules
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Match each ncRNA function to its correct description Guide
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Some ncRNAs function to deliver a molecule to a specific site
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Match each ncRNA function to its correct description Ribozyme
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Some ncRNAs have catalytic function
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Match each ncRNA function to its correct description Blocker
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Some ncRNAs prevent cellular processes from occurring
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Match each ncRNA function to its correct description Decoy
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Some ncRNAs bind to other ncRNAs and sequester them
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ncRNAs that contain binding sites for multiple components can act as a(n) ...... for the formation of a complex.
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scaffold
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An ncRNA that binds to a protein and brings it to a specific site in the cell's DNA is performing what function? Multiple choice question. Blocker Scaffold Guide Ribozyme
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Guide
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Non-coding RNAs are ______. Multiple choice question. short RNA molecules RNA molecules that do not encode polypeptides mRNA molecules that are not translated
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RNA molecules that do not encode polypeptides
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Select the molecules to which ncRNAs commonly bind. Multiple select question. Proteins Small molecules mRNA Lipids DNA Carbohydrates
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Proteins Small molecules mRNA DNA
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Select functions commonly carried out by ncRNAs.
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Guide Ribozyme Decoy Alteration of protein function or stability Scaffold Blocker
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In this figure, what role is played by the ncRNA?
Multiple choice question.
Scaffold
Decoy
Blocker
Ribozyme
In this figure, what role is played by the ncRNA? Multiple choice question. Scaffold Decoy Blocker Ribozyme
answer
Scaffold
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The ncRNA shown is helping a protein find a specific location on this DNA molecule. The ncRNA is acting as a ______.
Multiple choice question.
decoy
blocker
guide
scaffold
The ncRNA shown is helping a protein find a specific location on this DNA molecule. The ncRNA is acting as a ______. Multiple choice question. decoy blocker guide scaffold
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guide
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When an ncRNA binds to a(n) ....... , it can alter its ability to act as a catalyst, or its ability to bind to another molecule.
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protein
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Select ways in which the binding of an ncRNA to a protein may affect the protein's function. Multiple select question. It may affect the ability of the protein to act as a catalyst. It may affect the sequence of the protein. It may affect the ability of the protein to bind another molecule. It may affect the stability of the protein.
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It may affect the ability of the protein to act as a catalyst. It may affect the ability of the protein to bind another molecule. It may affect the stability of the protein.
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Which ncRNA associates with proteins to direct the synthesis of certain polypeptides to the plasma membrane? Multiple choice question. HOTAIR SRP RNA snRNA snoRNA
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SRP RNA
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Select the molecules to which ncRNAs commonly bind. Multiple select question. Proteins Lipids Carbohydrates Small molecules DNA mRNA
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Proteins Small molecules DNA mRNA
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A precursor to living cells consisting of an aggregate of molecules and macromolecules that acquired a boundary is called a(n) ......
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protobiont
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Key features of ...... that made them possible precursors of living cells include a boundary separating their contents from the external environment, polymers containing information, and polymers with catalytic functions.
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protobionts
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Match the ncRNA with its function. TERC
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Facilitates the binding of telomerase to the telomere
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Match the ncRNA with its function. COLDAIR
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Alters chromatin structure, repressing transcription
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Match the ncRNA with its function. CRISPR RNA
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Guides an endonuclease to foreign DNA
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Match the ncRNA with its function. PIWI-interacting RNA
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Prevents the movement of transposable elements
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A period on earth when RNA molecules, but not DNA or proteins, were found within protobionts is known as the ...... ......
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RNA world
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What is a protobiont? Multiple choice question. A type of ncRNA A precursor to living cells A type of therapy involving ncRNAs A protein required for miRNA processing
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A precursor to living cells
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Select features that make protobionts possible precursors of living cells.
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Polymers inside the protobiont had catalytic functions. Polymers inside the protobiont contained information. A boundary separated the internal contents of the protobiont from the external environment. Protobionts developed the capability of self-replication.
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Select key functions carried out by RNA in an RNA world. Multiple select question. Catalytic function The ability to store information in its nucleotide base sequence Ability to form organelles Ability to serve as a transcript for DNA in the protobiont The capacity for self-replication
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Catalytic function The ability to store information in its nucleotide base sequence The capacity for self-replication
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The first macromolecule found in protobionts is thought to be ______. Multiple choice question. RNA DNA protein
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RNA
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RNA's ability to work as a ______ would be crucial in its self-replication role in an RNA world. Multiple choice question. guide blocker scaffold ribozyme
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ribozyme
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Following the RNA world, which role did DNA take over from RNA? Multiple choice question. Synthesis of proteins Long-term storage of information Catalysis of chemical reactions
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Long-term storage of information
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What new functions would early cells have experienced by the introduction of proteins? Multiple select question. Structural roles of proteins Greater self-replicative ability than RNA Greater catalytic ability than RNA Uptake of substances into living cells by membrane proteins
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Structural roles of proteins Greater catalytic ability than RNA Uptake of substances into living cells by membrane proteins
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Select the roles played by the ncRNA HOTAIR. Multiple select question. Direct binding to mRNAs to block translation Activation of gene transcription Repression of gene transcription Alteration of chromatin structure
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Repression of gene transcription Alteration of chromatin structure
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Select advantages of having both DNA and RNA in cells versus RNA alone. Multiple select question. RNA would be free to perform other functions. DNA is more complex than RNA. DNA is more stable than RNA. DNA could relieve RNA of its long-term storage role.
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RNA would be free to perform other functions. DNA is more stable than RNA. DNA could relieve RNA of its long-term storage role.
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The first macromolecule found in protobionts is thought to be ______. Multiple choice question. protein DNA RNA
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RNA
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What is the function of the ncRNA HOTAIR? Multiple choice question. Decoy Blocker Ribozyme Scaffold
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Scaffold
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Rank these molecules according to catalytic activity, placing the molecule with the greatest catalytic ability on top.
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1. Proteins 2. RNA 3.DNA
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The ncRNA Hox transcript antisense intergenic RNA is also known as .......
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HOTAIR
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HOTAIR binds to a region near a target gene that ______. Multiple choice question. contains many purines contains many pyrimidines contains mainly As and Ts contains mainly Gs and Cs
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contains many purines
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Following the RNA world, which role did DNA take over from RNA? Multiple choice question. Synthesis of proteins Catalysis of chemical reactions Long-term storage of information
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Long-term storage of information
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What type of molecules does HOTAIR help guide to their target genes? Multiple choice question. Histone-modifying complexes Kinases Ubiquitin ligases Endonucleases DNA-modifying complexes
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Histone-modifying complexes
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How does a HOTAIR complex bind to target genes?
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A portion of HOTAIR is complementary to a GA-rich region found near target genes.
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Select advantages of having both DNA and RNA in cells versus RNA alone. Multiple select question. DNA could relieve RNA of its long-term storage role. DNA is more stable than RNA. RNA would be free to perform other functions. DNA is more complex than RNA.
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DNA could relieve RNA of its long-term storage role. DNA is more stable than RNA. RNA would be free to perform other functions.
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What is the function of the ncRNA HOTAIR? Multiple choice question. Ribozyme Blocker Decoy Scaffold
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Scaffold
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Identify the roles of the protein LSD1 in the repression of transcription by HOTAIR. Multiple select question. Binds to 3' end of HOTAIR Binds to 5' end of HOTAIR Demethylates H3K27 Demethylates H3K4 Trimethylates H3K27
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Binds to 3' end of HOTAIR Demethylates H3K4
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The ncRNA Hox transcript antisense intergenic RNA is also known as .....
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HOTAIR
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HOTAIR binds to a region near a target gene that ______. Multiple choice question. contains mainly As and Ts contains many pyrimidines contains mainly Gs and Cs contains many purines
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contains many purines
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Why was C. elegans used as the experimental organism in experiments carried out by Mello and Fire?
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It is relatively easy to inject with RNA. Expression of many of its genes had already been established.
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Identify the roles of the PCR2 complex in the repression of transcription by HOTAIR.
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Trimethylates H3K27 Binds to 5' end of HOTAIR
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This figure shows the outcome of the in situ hybridization procedure measuring mex-3 mRNA carried out by Mello and Fire. Match each letter with the correct experimental treatment. Instructions
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A- Control B- Injected with mex-3 antisense RNA C- Injected with double-stranded RNA