DNA Replication

12 September 2022
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DNA Replication
DNA Replication
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the process of making identical copies of DNA before cell division
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Replication Origin
Replication Origin
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Specific sequence of DNA where DNA synthesis begins.
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Semiconservative replication
Semiconservative replication
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Each half of an original DNA molecule serves as a templete for a new strand, and the two new DNA molecules each have one old and one new strand.
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DNA helicase
DNA helicase
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An enzyme that unwinds the double helix of DNA and separates the DNA strands in preparation for DNA replication.
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DNA Polymerase
DNA Polymerase
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Enzyme involved in DNA replication that joins individual nucleotides to produce a DNA molecule
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RNA Primer
RNA Primer
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Sequence of RNA nucleotides bound to a region of single-stranded DNA to initiate DNA replication.
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leading strand
leading strand
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the strand of DNA that is continuously synthesized into the replication fork.
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lagging strand
lagging strand
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The strand that is synthesized away from the replication fork , in fragments using sections called Okazaki fragments.
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Okazaki fragments
Okazaki fragments
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Small fragments of DNA produced on the lagging strand during DNA replication, joined later by DNA ligase to form a complete strand.
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DNA ligase
DNA ligase
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enzyme which connects the individual okazaki fragments on the lagging strand by forming covalent bonds
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direction of replication
direction of replication
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5' to 3' direction; In DNA synthesis, DNA strands always elongate in a 5' to 3' direction.
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double helix
double helix
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The form of DNA, referring to its two strands wound into a spiral shape.
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Primase
Primase
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An enzyme that creates a short RNA primer for initiation of DNA replication.
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deoxyribonucleic acid
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A molecule that consists of nucleotide monomers used for transmitting genetic information from one generation to the next
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nucleic acid
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Macromolecules that includes DNA and RNA.
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nucleotide
nucleotide
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A subunit of nucleic acids formed from a simple sugar, a phosphate group, and a nitrogenous base.
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adenine
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A nitrogen base found in DNA and RNA. It pairs with thymine in DNA and with uracil in RNA
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guanine
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A nitrogen base found in both DNA and RNA; pairs only with cytosine.
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thymine
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A nucleotide that pairs with adenine. Found only in DNA.
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cytosine
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A nitrogenous base found in DNA and RNA; pairs with guanine
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hydrogen bond
hydrogen bond
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A weak chemical bond used to hold complementary base pairs together
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base pairs
base pairs
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Any of the pairs formed between complementary bases in the two nucleotide chains of DNA, such as A-T and C-G (DNA); A-U and C-G (RNA)
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replication fork
replication fork
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A Y-shaped region on a replicating DNA molecule where new strands are growing.