Course A2: Introduction To Animal Care Laws, Regulations And Policies At USC

24 July 2022
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question
Which of the following is a role of AAALAC?
answer
sponsors a voluntary accreditation program for animal care and use programs
question
Which of the following is false concerning prolonged restraint of animals?
answer
it can be justified simply as a convenience for the research staff.
question
How do staff members enroll in the medical surveillance program for individuals with animal contact?
answer
fill out the USC on-line health surveillance questionnaire
question
Which of the following is the most common occupational health problem among personnel who work with laboratory animals?
answer
development of allergies against animals
question
Which statement concerning non-survival surgery is true?
answer
If an animal undergoes non-survival surgery, the surgical site should be clipped and clean instruments should be used.
question
Which of the following statements about pithing as a method of euthanasia is false?
answer
it is a simple technique readily performed by untrained students.
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What must you do if you are bitten by a research animal at USC?
answer
Report the incident to your supervisor and go to the Workers Compensation clinic
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Which statement concerning survival experimental surgery is false?
answer
If the incision site on the skin is disinfected with iodine or chlorhexidine compounds, hair clipping is not necessary.
question
Which of the following is a reasonable definition of euthanasia?
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The act of killing animals by methods that induce rapid unconsciousness and death without pain or distress.
question
The term IACUC stands for what?
answer
Institutional Animal Care and Use Committee
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Which of these statements is true concerning the USDA Animal Welfare Act?
answer
They take precedence over guidelines produced by the Public Health Service, Department of Veterans Affairs, and other government agencies.
question
According to the Guide, social animals should be housed in pairs or groups whenever possible. Which of the following is not a good justification for housing animals by themselves?
answer
Convenience of the research and husbandry staff.
question
The NIH Guidelines for Recombinant DNA and Gene Transfer do not apply to which of the following types of experiments?
answer
inoculation of non-recombinant infectious agents into animals
question
In general, prior to making any significant changes in your use of animals, what must you do?
answer
Obtain IACUC approval.
question
Which of the following is true concerning exsanguination?
answer
It is a technique that should not be used on conscious animals because loss of large blood volumes produces anxiety.
question
What are the primary purposes of the "3R's" concept of Russell and Burch?
answer
Urge scientists to minimize use of animals and to minimize pain and distress caused by animal experiments.
question
Which parameter would not likely be part of an endpoint policy?
answer
number of animals approved by the IACUC for a particular protocol
question
Which of the following is not an example of replacement?
answer
The use of a new analgesic that provides better postoperative pain relief
question
A simple rule to prevent excess blood collection in an animal is to collect no more than what percentage of body weight as blood at one time?
answer
1%
question
Which of the following statements is true if an investigator wants to use a human clinical area for animal research?
answer
permission should be obtained from the IACUC and responsible clinical administrators.
question
Which of the following statements about the use of carbon dioxide for euthanasia is false?
answer
It is the preferred method of euthanatizing rabbits, dogs, cats, and primates.
question
The USDA AWA Regulations require the IACUC to do what two things regarding alternatives?
answer
Ensure that the principal investigator has considered alternatives to painful or distressing procedures, and review a written assurance that alternatives are not available.
question
Which of the following concerning euthanasia is not true?
answer
Physical methods of euthanasia are most desirable when used on conscious animals.
question
What does the term zoonoses refer to?
answer
diseases that are transmissible from animals to humans
question
Which of the following statements about the postoperative period is false?
answer
Postoperative analgesia is not generally needed in rodents.
question
Blood collections should be spaced far enough apart to prevent which of the following?
answer
shock due to low blood volume, and anemia.
question
Which reference document contains detailed guidelines for performing euthanasia on a variety of animals?
answer
The Report of the AWMA Guidelines for the Euthanasia of Animals
question
Cervical dislocation performed by hand can be performed on which of the following animals?
answer
Rats weighing less than 200 grams and rabbits weighing less than 1kg.
question
The IACUC's activities to ensure compliance benefit whom?
answer
the institution, the investigator, and the animals
question
Because they cannot vomit and are not prone to aspiration pneumonia, which of the following animals should not routinely be fasted prior to surgery?
answer
Rodents and rabbits
question
Which of the following euthanasia agents is recommended for use by itself on a conscious animal?
answer
pentobarbital
question
Which of the following statements concerning the use of carbon dioxide to euthanatize rodents is true?
answer
Compared to adults, neonates are resistant to low oxygen levels, and less susceptible to death by carbon dioxide inhalation.
question
Which of the following is not considered a physical method of euthanasia?
answer
pentobarbital overdose
question
Which of the following is a false statement concerning euthanasia of animals?
answer
physical methods are generally preferred over non-physical methods
question
Which of the following "Guides" is best used as a source of guidelines for animals housed in farm settings?
answer
The "Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching."
question
The Johns Hopkins Center for Alternatives to Animal Testing (CAAT), the Institute for In Vitro Sciences, and the European Center for Validation of Alternative Methods (ECVAM) are primarily interested in what area?
answer
Performing or sponsoring research into alternatives to animal use for research and testing
question
What are the two principal animal research regulatory documents used by the Public Health Service?
answer
The PHS Policy on Humane Care and Use of Laboratory Animals and the "Guide for the Care and Use of Laboratory Animals."
question
If primate chairing is proposed as a method of restraint, which of the following is false?
answer
The primates must be chaired indefinitely if no signs of distress are apparent
question
Injections of euthanasia agents into the heart may be performed in what group of animals below?
answer
Anesthetized, heavily sedated, or comatose animals only.
question
Which of the following are not allowed by USDA policy, unless the IACUC approves?
answer
Changes in animal ownership and movement of animals between facilities during the postoperative period.
question
Which of the following is a false statement concerning cervical dislocation?
answer
because it is a non-physical method, it can be approved by the IACUC without a scientific justification.
question
Which of the following would not be accepted by an IACUC as the sole justification for performing multiple major survival surgeries?
answer
cost saving
question
Unlike the USDA AWA regulations, PHS Policy applies to which animals?
answer
All invertebrate species used in research.
question
Which of the following is not an example of reduction?
answer
The use of a new anesthetic that provides better induction and a shorter recovery period.
question
The location (room) in which a surgery can be conducted is not dependent on which factor?
answer
Whether the funds are from the VA or from NIH
question
Why is proper training in euthanasia techniques so important?
answer
Improper technique can cause unnecessary pain and distress in animals.
question
The three R's of Russell and Burch stand for what?
answer
Replacement, reduction, and refinement
question
Prior to beginning any work involving research animals, an investigator must do which of the following?
answer
Fill out animal protocol forms describing all proposed procedures, and receive IACUC approval.