COGS 17 Homework 3

3 September 2022
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Beta Activity
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EEG while awake/active, 18-24 Hz, Very high frequency, very desynchronized
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Alpha Activity
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EEG while awake/relaxed, 8-12 Hz, Very high frequency, somewhat more synchronized than Beta
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Theta Activity
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EEG during Sleep 1, 4-7 Hz, Lower frequency, still quite irregular, somewhat more synchronized than Beta
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Delta Activity
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EEG during sleep 3&4, < 4Hz in less& more than 50%, Very low frequency, high voltage, very synchronized
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Spindle and K Complexes
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During Sleep 2, 2 types of intermittent bursts of high frequency or voltage, as brain settles into deeper sleep
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Slow Wave Sleep
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Another term for sleep 3 & 4. It's low frequency EEG and high synchronized activity
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REM (Rapid Eye Movement)
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Stage of sleep associated with dreams
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Paradoxical Sleep
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Another name for REM due to it's contradictory nature (active, desynchronized brain but paralyzed body )
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Atonia
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Condition in which pons suppresses motor signals sent to Cord, so muscle action prohibited
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PGO Wave
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Sequence of activation in Pons => (Lateral) Geniculate => Occipital Cortex that initiates dream sleep
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ACh
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Excitatory neurotransmitter released by PGO Wave to desynchronize brain
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90
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Duration(# of minutes) of one sleep cycle through Stages 1,2,3,4,3,2,REM
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REM Rebound
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Condition after sleep deprivation in which system attempts to enter "Dream" sleep more frequently
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Suprachiasmic Nucleus (SCN)
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Location in Hypothalamus of Circadian Clock
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Zeitgeber
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"Time Giver", a stimulus, such as bright sunlight, that can reset Circadian Clock
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Retino-Hypothalamic Path
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Path of Optic Nerve of collateral that connects special visual receptors in eye directly to clock
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Pineal Gland
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Gland that produces a hormone that impacts on Hypothalamus to increase sleepiness
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Melatonin
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The hormone from the Pineal Gland; can be taken as a sleep aid
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Basal Forebrain
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Forebrain structure (Anterior and Dorsal to Hypothalamus) that modifies arousal in cortex
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ACh
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Neurotransmitter released by Basal Forebrain that increases cortical arousal
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GABA
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Neurotransmitter released by Basal Forebrain that decreases cortical arousal
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Adenosine
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Chemical that builds up in cells, released as NT, inhibits release of ACh, promotes sleep
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Caffeine
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Stimulant that blocks receptors for Adenosine, allows continued cortical arousal
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Pre-Optic Area
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Nucleus of Hypothalamus critical in initiating sleep (also assesses & regulates body temperature)
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Raphe Nuclei
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Structure in Pons whose functions include shutting off REM Sleep
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5HT
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Neurotransmitter released by Raphe Nuclei; very low in slow wave sleep, very high at the end of REM
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Reticular Formation
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"Net" from Medulla and Pons, for widespread arousal of Forebrain, esp Thalamus and Basal Forebrain
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ACh & Glutamate
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Two neurotransmitters released by reticular formation to alert brain
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Locus Coeruleus
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("Dark Blue Place") An arousal center, active during new tasks, vigilance, memory formation
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Norepinepherine
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Neurotransmitter released by Locus Coeruleus, absent during dreams; Amphetamines are antagonists for these
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Organizing/Activating
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Effects of reproductive hormones on anatomy VS. on behavior
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Estrogen/Androgens
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Class of reproductive hormones found in greater portion in females VS. in males
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X/Y
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Sex chromosomes typical of females VS. males; helps determine gender
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Wolffian/Muellerian
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Systems of ducts in fetus that become part of internal reproductive organs of males VS. females
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Testosterone
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A male hormone, produced by testes, responsible for development of male anatomy and behavior
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Anti-Muellerian
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Another male hormone that inhibits development of female system of internal ducts
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Testes Determining Factor
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Enzyme produced by "switch" on male chromosome that leads to the development of gender
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Androgen Insensitive
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Condition in which genetic-male fetus does not respond to male hormones and thus develops as female
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Turner's Syndrome
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Condition in which fetus lacks Y chromosome, develops internally and externally as infertile female
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Estradiol
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A female hormone,(similar to testosterone) that, once inside fetal cells, promotes MALE development
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Alpha-Fetoprotein
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Chemical in fetal blood that prevents mother's hormones from entering fetal cells and masculinizing fetus
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Medial Preoptic Area (MPOA)
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Area of Hypothalamus w/ receptor sites for male hormones esp active during male sexual behavior
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Sexually Diamorphic Nucleus (SDN)
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MPOA includes this nucleus which is 2.5x larger in males than females
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INAH3
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Part of SDN that is smaller both in females and in homosexual men
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Ventro-Medial Hypothalamus (VMH)
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Area of Hypothalamus w/ receptor sites for female hormones, esp active during female sexual behavior
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Corpus Callosum
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Fibers connecting coritcal hemispheres which is thicker in females, who are thus less-lateralized
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GnRH
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Hormones released by Hypothalamus causing Anterior Pituitary to release its reproductive hormones
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LH & FSH
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Two Gonadotropic hormones that stimulate development and behavior in both genders
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Androstenedione
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Male hormone released by female adrenal glands, stimulates secondary hair growth and sexual behavior
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Nucleus Accumbens
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Area near Basal Forebrain associated with the sensation of sexual pleasure
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Dopamine
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Neurotransmitter released by Nucleus Accumbens in response to sexual stimulation
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Oxytocin
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Hormone released by Posterior Pituitary at time of orgasm
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Prolactin
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Hormone released by Anterior Pituitary for refractory period in males and milk production in females
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Periaqueductal Gray Area
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Part of Tegmentum active especially in Females during sex
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Endorphins
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Neurotransmitter released by Periaqueductal Gray Area, suppresses potential for pain
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James-Lange
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Theory that suggests emotion is an after-the-fact label we give to arousal and associated behavior
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Cannon-Bard
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Theory: Once threat is perceived (via Thalamus), emotion is simultaneous ANS activity and subjective experience
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Papez Circuit
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Update of Cannon-Bard Theory that includes the Limbic System in circuit
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Schacter-Singer
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Theory: Emotion is interaction between cognitive appraisal and autonomic/limbic activity
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Amygdala
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Key Limbic structure implicated in interpreting valenced situations and coordinating an emotional response
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Corticomedial
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Area of Amygdala that promotes an attack when stimulated
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Lateral
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Area of Amygdala responsible for the Startle Reflex
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Central and Basolateral
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Areas of Amygdala involved in Conditioned Fear and subsequent enhancement of Startle Reflex
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Urbache-Weithe
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Degenerative calcium buildup in Amygdala that results in deficits in interpreting facial expressions
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Frontal Cortex
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Area of cortex w. reciprocal connections to Amygdala; involved in expressing, inhibiting and reading emotion
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Phineas Gage
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Famous Patient with damage to Frontal Cortex from a railway building accident
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Theory of Mind
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Capacity to attribute mental states to others. Probably mediated by late-developing Prefrontal-Amygdala links
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Helplessness
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Prefrontal assessment of a negative situation that one is powerless to affect. Can lead to Parasympathetic Rebound ulcers
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Anterior Insular Cortex
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Ventral, Medial area of anterior Temporal Lobes involved in facial expression and (taste) reaction of disgust
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Emotional Facial Paresis
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Result of damage to AIC involving deficit in ability to spontaneously smile
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Volitional Facial Paresis
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Result of damage to Motor Cortex for facial region that involves a deficit in voluntarily showing teeth
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Gambling Task
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Common task used in lab to assess risk aversion; tests anxiety
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Serotonin Turnover
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NT whose low turnover level is associated w/ impulsiveness, aggression, and depression
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CCK
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Excitatory NT associated with enhanced Startle Reflex
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GABA
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Inhibitory NT, admits Cl- ions into cells. Agonists (Valium/Xanax) are used to combat anxiety
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Law of Effect
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Rule of Conditioning: Event associated with +/- reinforcement will/will not be repeated
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Classical conditioning
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Developed association between stimuli, especially involving an unconditioned response
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Operance Conditioning
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Developed association between stimulus and response
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Hebbian Cell Assemblies
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Co-activated neural circuits presumably involved in learning and retrieval of associations
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Long term potentiation
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Physical changes in cells involved in Hebbian Cell Assemblies. associated with learning
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Hippocampus
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Area of brain in which Long Term potentiation has been well studied/described
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Glutamate
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Type of NT involved in LTP
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AMPA
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Type of receptor site for glutamate that is ionotropic and easy to stimulate
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NMDA
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Type of receptor site for Glutamate that is difficult to stimulate and often requires hypo-polarization
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Mg++
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Type of ion that blocks ion gate of NMDA
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AMPA
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Type of receptor site that NMDA changes into after repeated co-activity in a curcuit
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Dendritic Branches
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One kind of change to dendrite structure that results in an increase in surface area and this of available sites
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Perforation
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Act by post-synaptic cell membrane that results in an increase in surface area and thus of available sites
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Genetic changes
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DNA transcribed to RNS translated to protein production that increases likelihood of neural activity
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Neurogenesis
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Rare(except in hippocampus) generation of new neurons associated with learning
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Spatial
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Recall of specific locations, spatial judgements of familiarity
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Hippocampus
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Area of brain in which Spatial memory has been well studied/described
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Procedural
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Motor Skill; How to do it (peck a target, ride a bike)
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Cerebellum and Striatum
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Areas of brain where Procedural memory has been well studied/described
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Declarative
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Episodic (personal history) and Semantic/Associative (facts) memory
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Hippocampus and Mediodorsal Thalamus
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Areas of brain where Declarative memory has been well studied/described
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Place Cells
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Types of cells found in hippocampus whose activity becomes associated with particular parts of a familiar environment
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Cognitive Map
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The type of map formed by a subject who gets to know the spatial layout of a particular environment
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Lateral Interpositus
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Subsection of Cerebellum associated with conditioning of "eye blink" response
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Red Nucleus
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Area of Tegmentum(in midbrain) that also plays a role in "eye blink response"
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Match to Sample
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Task requiring application of rule "Pick alternative that is the same as the sample stimulus"
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Hippocampus
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Area lesioned in rats caused impairment on Match to Sample
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Mediodorsal Thalamus
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Area that projects to Prefrontal Cortex implicated in declarative memory
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Prefrontal Cortex
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Area of Cortex associated with "working memory" especially when response delays are involved
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Korsakoffs Syndrome
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Syndrome from B1 deficiency via chronic alcoholism that especially affects cells of Prefrontal Cortex
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Anterograde Amnesia
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Type of memory deficit most commonly associated with Korsakoffs syndrome; inability to generate new memories
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Confabulation
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Symptom of Anterograde Amnesia involving tale-telling in which imagination is not distinguishable from knowledge
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H.M.
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Famous patient with damage to hippocampus and other temporal areas
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Declarative
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Type of learning/memory H.M. cannot form
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Working memory
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No deficits shown for this in H.M.
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Amygdala
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Limbic Structure that plays a role in learning such as "conditioned fear" and arousal in "taboo"
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Prosopagnosia
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Deficit in ability to recognize(remember) faces
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Fusiform Gyrus
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Area of brain associated with Inferior Temporal Cortex where presumably relevant data are stored
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Dorsal Temporal Cortex
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Area of brain where well-learned voices, words are "stored"
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Lateralization
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Dominance of one cerebral hemisphere over the other for particular functions
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Wada Test
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Test in which one hemisphere is anesthetized to test for capacity/speed of processing of other
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Planum Temporale
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Area in left temporal cortex larger in most humans(& in some other primates) associated with language processing
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Interference
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Cognitive principle that like-disrupts-like (e.g. left hemisphere activated by language)
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Corpus Callosum
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Main bundle of axons connecting two hemispheres
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Split Brain Patient
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Patient in whom Corpus Callosum have been severed (as in treatment for epilepsy)
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Anterior Commisure
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Additional inter-hemisphere connection between anterior cortex, especially of temporal lobes
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Left Hemisphere
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Hemisphere dominant for most language processing
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Broca's Area
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Area associated with language production
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Frontal Cortex
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Location of Broca's Area
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Broca's Aphasia
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Type of Aphasia associated with damage to Broca's Area
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Articulation Difficulties
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One type of difficulty in Broca's Aphasia; speech is slowed and halting
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Agrammatism
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Another deficit involving word order and the use of syntax markers
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Closed Class
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The fixed class of terms that organize syntactical relations such as prepositions, articles, conjunctions, etc.
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Anomia
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Deficit involving difficulty in "finding" words especially closed class
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Sign Language Production
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Deficit in one aspect of the "language of the deaf" associated with anomia
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Wernike's Area
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Area associated with language comprehension
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Temporal lobe
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Location of Wernike's area
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Wernike's Aphasia
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Type of aphasia associated with damage to Wernike's area
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Fluency
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Unlabored speech, with normal prosody as seen in Wenicke's area
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Content Terms
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Open (changeable) class of terms that includes nouns and verbs
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Pure word deafness
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Deficit in which patient cannot understand spoken words at all (even if they can read/write)
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Nonsensical Speech
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Deficit involving using irrelevant or made-up words
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Sign language Comprehension
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Aspect of language of the deaf NOT affected by damage to STS and Parietal Lobe
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Parietal Lobe
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Cortical area in which damage would result in affecting Sign Language Production
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Arcuate Fasiculus
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Fibers that connect the areas involved in production and comprehension of speech
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Conduction Aphasia
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Type of Aphasia associated with damage to Arcuate Fasiculus
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Phonemic Paraphasia
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Deficit in which similar sounding words, but with different meanings, are substituted during attempt to repeat
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Phonological Loop
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Aspect of working memory involving rehearsal that is probably important normal function of these conditions
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Right Hemisphere
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Global Pattern Recognition, Spatial and Socio-Economic are specializations of this hemisphere
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Global Pattern Recognition
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Ability to get the "gist", to see the "larger picture", to organize narrative, etc
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Spatial
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Abilities involved in learning, remembering and navigating environments
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Socio-Emotional
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Abilities involved in facial and nonverbal expression and interpretation
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Music
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Domain in which Global Pattern Recognition, Spatial and Socio-Economic abilities come into play in the aesthetic organization of sound