The specificity of an antibody is due to:
the L chains.
the constant portions of the H and L chains.
its valence.
the variable portions of the H and L chains.
the H chains.
answer
the variable portions of the H and L chains.
question
Which of the following is NOT a characteristic of cellular immunity?
It can inhibit the immune response.
Cells are processed in the thymus gland.
B cells make antibodies.
The cells originate in bone marrow.
T cells react with antigens.
answer
B cells make antibodies.
question
The antibodies found in mucus, saliva, and tears are primarily:
IgE.
IgD.
IgA.
IgG.
IgM.
answer
IgA
question
In addition to IgG, the antibodies that can fix complement are:
None of the answers are correct.
IgE.
IgD.
IgM.
IgA.
answer
IgM
question
Which of the following destroys virus-infected cells?
T(reg)
dendritic cells
T(H)
B cells
CTL
answer
CTL
question
Which of the following statements about natural killer cells is FALSE?
They destroy tumor cells.
They destroy virus-infected cells.
They destroy cells lacking MHC I.
They are stimulated by antigen from infectious agents.
None of the answers are correct; all of these statements are true
answer
They are stimulated by antigen from infectious agents.
question
A Treg cell deficiency could result in:
increased number of bacterial infections.
autoimmunity.
increased number of viral infections.
increased severity of bacterial infections.
transplant rejection.
answer
autoimmunity.
question
ADCC is a process that is most effective in destroying:
eukaryotic parasites
bacterial pathogens.
bacterial toxins.
prions.
extracellular viruses.
answer
eukaryotic parasites
question
MOST antigens are composed of:
nucleic acids or lipids
proteins or large polysaccharides.
proteins or lipids.
lipids or large polysaccharides.
answer
proteins or large polysaccharides.
question
IgG antibodies that inactivate microbes by blocking their attachment to host cells is the process of:
apoptosis.
agglutination.
neutralization.
opsonization.
answer
neutralization.
question
The FIRST antibody B cells make during primary response to an infection is:
IgA.
IgE.
IgM.
IgG.
answer
IgM
question
A person who has measles will develop ________ immunity.
naturally acquired passive
artificially acquired passive
artificially acquired active
naturally acquired active
answer
naturally acquired active
question
What type of immunity is conveyed when exposed individuals are given antibodies by injection?
artificially acquired passive immunity
naturally acquired passive immunity
artificially acquired active immunity
naturally acquired active immunity
answer
artificially acquired passive immunity
question
A person has been sick less than one week and comes to the clinic with fever and yellow skin. The doctor requests a serology test for hepatitis A. Which type of antibodies should be detected during this acute infection?
IgG
IgD
IgE
IgA
IgM
answer
IgM
question
A 60-year-old patient presents at the clinic with a painful rash on the left side of his torso. The doctor orders a serology test against herpes zoster virus. What type of antibodies should be measured?
IgD
IgE
IgA
IgM
IgG
answer
IgG
question
Which type of antibodies cross the placenta?
IgE
IgG
IgA
IgD
IgM
answer
IgG
question
Patients infected with HIV and with active AIDS have low levels of CD4+ cells, which are TH cells. These patients are immunodeficient because ______________ to fight off infections
they do not have helper cells to promote B cells and cytotoxic T cells to mature
they do not have enough cells to make antibodies
they are missing natural killer cells
they cannot make IgM antibodies
answer
they do not have helper cells to promote B cells and cytotoxic T cells to mature
question
Macrophages can recognize antibodies bound to the surface of bacteria by recognizing _______ on immunoglobulins. This process induces phagocytosis and is called ____________
Fc regions, antibody-dependent cellular cytotoxicity (ADCC)
Fc regions, opsonization
Fc regions, agglutination
Fab regions, agglutination
Fab regions, opsonization
answer
Fc regions, opsonization
question
In Figure 17.1, which letter on the graph indicates the patient's secondary response to a repeated exposure with the identical antigen?
c
a
e
b
answer
c
question
Opsonization
answer
antibody enhancement of phagocytosis
question
Agglutination
answer
Antibody clumping of bacteria
question
Neutralization
answer
antibodies binding to toxins to interfere with function
question
ADCC
answer
Antibody dependent cellular killing
question
Membrane attack lysis
answer
bound antibody activating complement
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