In a centrifuged sample of blood, what makes up the buffy coat?
plasma
red blood cells
white blood cells and platelets
platelets only
answer
white blood cells and platelets
question
Which of the following is NOT a function of blood?
regulation
distribution
protection
hormone production
answer
hormone production
question
The __________ is the fluid portion of the blood.
hematocrit
plasma
buffy coat
hemoglobin
answer
Plasma
question
The majority of whole blood is __________.
erythrocytes
leukocytes
platelets
plasma
answer
Plasma
question
What does dark red blood indicate?
oxygen-poor blood
saltiness of blood
pH of blood
oxygen-rich blood
answer
oxygen-poor blood
question
Which plasma constituent is the main contributor to osmotic pressure?
fibrinogen
beta globulins
albumin
alpha globulins
answer
albumin
question
The main protein in blood plasma is __________.
erythropoietin
plasmin
albumin
hemoglobin
answer
Albumin
question
Athletes who choose to use industry-produced EPO as a performance-enhancing drug to increase the effects of their naturally-produced EPO, will experience ______.
decreased production of EPO by their kidneys
decreased erythropoiesis
decreased reticulocyte counts
None of the listed responses is correct.
answer
decreased production of EPO by their kidneys
question
In a cancer patient undergoing chemotherapy, the decision to utilize a CSF capable of specifically stimulating the production of only the granular leukocytes would require that the CSF acts exclusively on ______.
lymphoid stem cells
myeloid stem cells
myeloblasts
lymphoblasts
answer
myeloblasts
question
Which of the formed elements contains hemoglobin and transports respiratory gases?
granular leukocytes
platelets
erythrocytes
agranular leukocytes
answer
erythrocytes
question
Which of the following is NOT a functional characteristic of leukocytes?
leukocytosis
positive chemotaxis
diapedesis
amoeboid motion
answer
leukocytosis
question
Which leukocyte functions in phagocytizing bacteria?
neutrophil
lymphocyte
basophil
eosinophil
answer
neutrophil
question
Which of the following is NOT a formed element of the blood?
leukocytes
erythrocytes
platelets
antibodies
answer
antibodies
question
Choose the statement that is true concerning hemoglobin.
It is composed of four protein chains and four heme groups.
When hemoglobin is not bound to oxygen, it appears blue.
It can bind a maximum of three oxygen molecules.
It is found in the plasma portion of blood.
answer
It is composed of four protein chains and four heme groups.
question
In adults, red blood cell production occurs in __________.
the liver
yellow bone marrow
red bone marrow
the thymus
answer
red bone marrow
question
Which of the following does NOT stimulate erythrocyte production?
erythropoietin
hyperventilating
a drop in normal blood oxygen levels
testosterone
answer
hyperventilating
question
Bilirubin is cleared from the body by __________.
the liver
the pancreas
the kidneys
the spleen
answer
the liver
question
Which of the following is correctly matched?
hemorrhagic anemia: red blood cells rupture
aplastic anemia: results from excessive blood loss
pernicious anemia: results from a vitamin B12 deficiency
hemolytic anemia: results from inadequate iron intake
answer
pernicious anemia: results from a vitamin B12 deficiency
question
An abnormal excess of erythrocytes is called __________.
thalassemia
sickle-cell anemia
leukocytosis
polycythemia
answer
polycythemia
question
The most abundant leukocytes are __________.
neutrophils
monocytes
lymphocytes
basophils
answer
neutrophils
question
On a blood smear slide prepared using Wright's stain, you observe a large cell with a U-shaped nucleus and pale blue cytoplasm. This cell is most likely a(n) __________.
lymphocyte
basophil
monocyte
eosinophil
answer
monocyte
question
Platelet formation is regulated by __________.
plasmin
thrombopoietin
erythropoietin
interleukin-2
answer
thrombopoietin
question
Erythrocytes lack a nucleus.
True
False
answer
True
question
All leukocytes are also lymphocytes.
True
False
answer
False
question
When a person has an acute bacterial infection, such as meningitis or appendicitis, which type of leukocyte increases in number?
basophils
eosinophils
neutrophils
lymphocytes
answer
Neutrophils
question
Which type of leukocyte is responsible for antibody production?
basophils
eosinophils
neutrophils
lymphocytes
answer
Lymphocytes
question
When we take anti-histamines, we are countering the effects of which type of leukocyte?
lymphocytes
neutrophils
basophils
eosinophils
answer
basophils
question
What do the lymphoid stem cells give rise to?
monocytes
erythrocytes
granulocytes
lymphocytes
answer
lymphocytes
question
Which cell of the myeloid stem cell pathway has accumulated granules?
myeloblasts
myelocytes
monocytes
promyelocytes
answer
myelocytes
question
From which cell do the granulocytes descend?
lymphoid stem cell
monoblast
myeloblast
promonocyte
answer
myeloblast
question
What part of the pathway to produce platelets is shared with other formed elements?
reticulocyte
hematopoietic stem cell (hemocytoblast)
lymphoid stem cell
megakaryoblast
answer
hematopoietic stem cell (hemocytoblast)
question
Which formed element can be described as cytoplasmic fragments?
lymphocytes
monocytes
platelets
erythrocytes
answer
platelets
question
Which of the following is true of the structure of an erythrocyte?
answer
Erythrocytes are shaped like biconcave discs.
question
What is the name of the protein found in erythrocytes that allows for respiratory gas transport?
answer
Hemoglobin
question
What triggers erythropoietin (EPO) production to make new red blood cells?
answer
Reduced Availability of Oxygen
question
Which part of the hemoglobin molecule binds carbon dioxide for transport?
answer
amino acids of globin
question
How many oxygen molecules can be transported by one hemoglobin molecule?
answer
Four
question
When oxygen is bound to hemoglobin, what bright red molecule is formed?
answer
Oxyhemoglobin
question
Specifically, what is the production of red blood cells called?
answer
erythropoiesis
question
What is a young, anucleate erythrocyte called?
answer
reticulocyte
question
What part of the body does erythropoietin (EPO) target to increase erythropoiesis?
answer
Bone Marrow
question
What part of the hemoglobin molecule is recycled to form bile?
answer
a portion of the heme group
question
What erythrocyte production disorder results from an autoimmune disease associated with vitamin B12 absorption?
answer
pernicious anemia
question
What role do the kidneys play in erythropoiesis?
answer
The kidneys detect low levels of oxygen in the blood.
question
Which of the following is NOT a part of hemostasis?
answer
vascular relaxation
question
What protein involved in coagulation provides the scaffolding for tissue repair?
answer
Fibrin
question
What is an embolus?
answer
a blood clot that has broken loose and is floating freely in the bloodstream
question
Hemostasis leads to __________.
answer
Stoppage of bleeding
question
The first step in hemostasis is __________.
answer
Vascular Spasm
question
Which of the following represents a difference between extrinsic and intrinsic blood clotting pathways?
answer
One is faster than the other
question
The enzyme __________ digests fibrin clots.
answer
Plasmin
question
Which of the following would NOT lead to a bleeding disorder?
answer
Excess calcium in the Diet
question
Which of the following is best suited to the clotting process that occurs when blood vessels are ruptured?
answer
Platelets
question
Which event of hemostasis constricts the damaged artery to reduce blood loss? Select from letters A-D.
answer
A.
question
During which event of hemostasis do clotting factors (procoagulants) assist with the transformation of blood from a liquid to a gel? Select from letters A-D.
answer
D.
question
What "clot buster" enzyme removes unneeded clots after healing has occurred during fibrinolysis?
answer
Plasmin
question
During erythroblastosis fetalis, a Rh- mother's anti-Rh antibodies that have crossed the placenta will cause agglutination of the fetus's Rh+ RBCs. However, the reverse problem never happens when a Rh+ mother is pregnant with a Rh- fetus, that is, antibodies produced by the fetus cannot cause agglutination of the mother's Rh+ RBCs. This is true because ______.
answer
antibodies that can cause this agglutination are not produced by a fetus
question
Which ABO blood type is considered to be the universal donor?
answer
O
question
A person who lacks agglutinogens A and B would have blood type __________.
answer
O
question
Which of the following scenarios could result in HDN (hemolytic disease of the newborn)?
answer
B- female pregnant with an AB+ baby
question
Choose the compatible transfusion.
answer
Donate type O blood to a recipient with type AB blood.
question
A person's blood type is genetically determined.
answer
True
question
What is hematocrit a measure of?
answer
Hematocrit is the percentage of erythrocytes in a whole blood sample.
question
Which of the following does NOT serve as a site for blood cell production in the developing fetus?
answer
Intestines
question
What is the average normal pH range of blood?
answer
7.35-7.45
question
Which of the following is not a distribution function of blood?
answer
Transport of salts to maintain blood volume
question
Which of the following is a protective function of blood?
answer
Prevention of Blood Loss
question
Which of the following statements does not describe blood?
answer
Blood carriers body cells to injured areas for repair
question
Which of the following is true about blood plasma?
answer
It is abut 90% water
question
The plasma protein that is the major contributor to osmotic pressure is ________.
answer
Albumin
question
The primary source of RBCs in the adult human being is the bone marrow in the shafts of the long bones.
answer
False
question
Hemorrhagic anemias result from blood loss.
answer
True
question
White blood cells are produced through the action of colony-stimulating factors.
answer
True
question
Hemoglobin is made up of the protein heme and the red pigment globin.
answer
False
question
Each hemoglobin molecule can transport two molecules of oxygen.
answer
False
question
Diapedesis is the process by which red blood cells move into tissue spaces from the interior of blood capillaries.
answer
False
question
Positive chemotaxis is a feedback system that signals leukocyte migration into damaged areas.
answer
True
question
Basophils increase in number when parasitic invasion occurs.
answer
False
question
Leukopenia is an abnormally low number of leukocytes.
answer
True
question
Leukocytes move through the circulatory system by amoeboid motion.
answer
False
question
Granulocytes called neutrophils are phagocytic and are the most numerous of all white blood cell types.
answer
True
question
All lymphocytes are leukocytes, but not all leukocytes are lymphocytes.
answer
True
question
Myelocytic leukemia involves a cancerous condition of lymphocytes.
answer
False
question
Which of the following might trigger erythropoiesis?
answer
hypoxia of EPO-producing cells
question
James has a hemoglobin measurement of 16 g/100 ml blood. This is ________.
answer
Within Normal Range
question
All of the following can be expected with polycythemia except ________.
answer
low blood viscosity
question
No visible cytoplasmic granules are present in ________.
answer
Monocytes
question
Which of the following is characteristic of all leukocytes?
answer
They are nucleated
question
Platelets ________.
answer
stick to the damaged area of a blood vessel and help seal the break
question
Complications of aplastic anemia generally do not include ________.
answer
increase of leukocytes as a result of erythrocyte loss
question
What organ in the body regulates erythrocyte production?
answer
Kidney
question
Leukemia refers to cancerous conditions involving white blood cells.
answer
True
question
The normal RBC "graveyard" is the liver.
answer
False
question
Myeloid stem cells give rise to all leukocytes.
answer
False
question
Which of the following is not a functional characteristic of WBCs?
answer
granulosis
question
Which of the choices below is the parent cell for all formed elements of blood?
answer
hemocytoblast
question
Blood reticulocyte counts provide information regarding ________.
answer
rate of erythrocyte formation
question
Select the incorrect statement regarding blood cell formation.
answer
Platelets are formed from myeloblasts
question
Which of the following is not a structural characteristic that contributes to erythrocyte gas transport functions?
answer
mitotically active
question
A lack of intrinsic factor, leading to a deficiency of vitamin B12 and causing an appearance of large pale cells called macrocytes, is characteristic of ________.
answer
pernicious anemia
question
Which of the following would not be a possible cause of sickling of red blood cells in someone with sickle-cell anemia?
answer
Sleeping in a well ventilated room
question
The immediate response to blood vessel injury is clotting.
answer
False
question
Which of the following is not a phase of hemostasis?
answer
fibrinolysis
question
The slowest step in the clotting process is ________.
answer
formation of prothrombin activator
question
Thromboembolic disorders ________.
answer
include embolus formation, a clot moving within the circulatory system
question
Which of the following is not a cause of bleeding disorders?
answer
excess secretion of platelet-derived growth factor (PDGF)
question
Which sequence is correct for the following events?
1. fibrinogen β fibrin
2. clot retraction
3. formation of thromboplastin
4. prothrombin β thrombin
answer
3, 4, 1, 2
question
All of the following conditions impair coagulation except ________.
answer
vascular spasm
question
The process of fibrinolysis disposes of bacteria when healing has occurred.
answer
False
question
Clotting factor activation turns clotting factors into enzymes.
answer
True
question
A person with type B blood could receive blood from a person with either type B or type O blood.
answer
True
question
An individual who is blood type AB negative can ________.
answer
receive any blood type in moderate amounts except that with the Rh antigen
question
Blood volume restorers include all of the following except ________.
answer
packed cells
question
Fred's blood was determined to be AB positive. What does this mean?
answer
There are no antibodies to A, to B, or to Rh antigens in the plasma.
question
When can erythroblastosis fetalis not possibly happen in the child of an Rh negative mother?
answer
f the father is Rh-
question
Why would there be cause for concern if a young pregnant mother is Rh-, her husband is Rh+, and this is their second child?
answer
If the second child is Rh+ and the mother did not take RhoGAM, there is a chance that the child will develop erythroblastosis fetalis and die before birth
question
Which blood type is generally called the universal donor?
answer
O
question
Which of the statements below is an incorrect or false statement?
answer
Blood typing for the Kell, Lewis, and Duffy factors is always done before a blood transfusion.
question
When neither anti-A serum nor anti-B serum cause clumping (agglutination) of donor cells on a slide, the blood type is ________.
answer
O
question
A total WBC count and a differential WBC count have been ordered for Mrs. Johnson. What information is obtained from the differential count that the total count does not provide?
answer
The differential count determines the relative proportion of individual leukocyte types. The total WBC count indicates an increase or decrease in number of WBCs.
question
A patient complains of no energy, a chronic sore throat, a low-grade fever, and is tired and achy. His doctor notes an enlarged spleen upon examination. What diagnosis would you expect, and what definitive test would you request?
answer
The diagnosis is infectious mononucleosis. The test would be a differential white blood cell count to look for elevated numbers of monocytes and atypical lymphocytes.
question
The special type of hemoglobin present in fetal red blood cells is ________.
answer
hemoglobin F
question
Fetal hemoglobin has a higher affinity for oxygen than does adult hemoglobin.
answer
True
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