Ch. 17

25 July 2022
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question
In a centrifuged sample of blood, what makes up the buffy coat? plasma red blood cells white blood cells and platelets platelets only
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white blood cells and platelets
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Which of the following is NOT a function of blood? regulation distribution protection hormone production
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hormone production
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The __________ is the fluid portion of the blood. hematocrit plasma buffy coat hemoglobin
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Plasma
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The majority of whole blood is __________. erythrocytes leukocytes platelets plasma
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Plasma
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What does dark red blood indicate? oxygen-poor blood saltiness of blood pH of blood oxygen-rich blood
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oxygen-poor blood
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Which plasma constituent is the main contributor to osmotic pressure? fibrinogen beta globulins albumin alpha globulins
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albumin
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The main protein in blood plasma is __________. erythropoietin plasmin albumin hemoglobin
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Albumin
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Athletes who choose to use industry-produced EPO as a performance-enhancing drug to increase the effects of their naturally-produced EPO, will experience ______. decreased production of EPO by their kidneys decreased erythropoiesis decreased reticulocyte counts None of the listed responses is correct.
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decreased production of EPO by their kidneys
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In a cancer patient undergoing chemotherapy, the decision to utilize a CSF capable of specifically stimulating the production of only the granular leukocytes would require that the CSF acts exclusively on ______. lymphoid stem cells myeloid stem cells myeloblasts lymphoblasts
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myeloblasts
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Which of the formed elements contains hemoglobin and transports respiratory gases? granular leukocytes platelets erythrocytes agranular leukocytes
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erythrocytes
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Which of the following is NOT a functional characteristic of leukocytes? leukocytosis positive chemotaxis diapedesis amoeboid motion
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leukocytosis
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Which leukocyte functions in phagocytizing bacteria? neutrophil lymphocyte basophil eosinophil
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neutrophil
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Which of the following is NOT a formed element of the blood? leukocytes erythrocytes platelets antibodies
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antibodies
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Choose the statement that is true concerning hemoglobin. It is composed of four protein chains and four heme groups. When hemoglobin is not bound to oxygen, it appears blue. It can bind a maximum of three oxygen molecules. It is found in the plasma portion of blood.
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It is composed of four protein chains and four heme groups.
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In adults, red blood cell production occurs in __________. the liver yellow bone marrow red bone marrow the thymus
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red bone marrow
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Which of the following does NOT stimulate erythrocyte production? erythropoietin hyperventilating a drop in normal blood oxygen levels testosterone
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hyperventilating
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Bilirubin is cleared from the body by __________. the liver the pancreas the kidneys the spleen
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the liver
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Which of the following is correctly matched? hemorrhagic anemia: red blood cells rupture aplastic anemia: results from excessive blood loss pernicious anemia: results from a vitamin B12 deficiency hemolytic anemia: results from inadequate iron intake
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pernicious anemia: results from a vitamin B12 deficiency
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An abnormal excess of erythrocytes is called __________. thalassemia sickle-cell anemia leukocytosis polycythemia
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polycythemia
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The most abundant leukocytes are __________. neutrophils monocytes lymphocytes basophils
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neutrophils
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On a blood smear slide prepared using Wright's stain, you observe a large cell with a U-shaped nucleus and pale blue cytoplasm. This cell is most likely a(n) __________. lymphocyte basophil monocyte eosinophil
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monocyte
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Platelet formation is regulated by __________. plasmin thrombopoietin erythropoietin interleukin-2
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thrombopoietin
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Erythrocytes lack a nucleus. True False
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True
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All leukocytes are also lymphocytes. True False
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False
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When a person has an acute bacterial infection, such as meningitis or appendicitis, which type of leukocyte increases in number? basophils eosinophils neutrophils lymphocytes
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Neutrophils
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Which type of leukocyte is responsible for antibody production? basophils eosinophils neutrophils lymphocytes
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Lymphocytes
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When we take anti-histamines, we are countering the effects of which type of leukocyte? lymphocytes neutrophils basophils eosinophils
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basophils
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What do the lymphoid stem cells give rise to? monocytes erythrocytes granulocytes lymphocytes
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lymphocytes
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Which cell of the myeloid stem cell pathway has accumulated granules? myeloblasts myelocytes monocytes promyelocytes
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myelocytes
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From which cell do the granulocytes descend? lymphoid stem cell monoblast myeloblast promonocyte
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myeloblast
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What part of the pathway to produce platelets is shared with other formed elements? reticulocyte hematopoietic stem cell (hemocytoblast) lymphoid stem cell megakaryoblast
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hematopoietic stem cell (hemocytoblast)
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Which formed element can be described as cytoplasmic fragments? lymphocytes monocytes platelets erythrocytes
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platelets
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Which of the following is true of the structure of an erythrocyte?
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Erythrocytes are shaped like biconcave discs.
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What is the name of the protein found in erythrocytes that allows for respiratory gas transport?
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Hemoglobin
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What triggers erythropoietin (EPO) production to make new red blood cells?
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Reduced Availability of Oxygen
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Which part of the hemoglobin molecule binds carbon dioxide for transport?
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amino acids of globin
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How many oxygen molecules can be transported by one hemoglobin molecule?
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Four
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When oxygen is bound to hemoglobin, what bright red molecule is formed?
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Oxyhemoglobin
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Specifically, what is the production of red blood cells called?
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erythropoiesis
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What is a young, anucleate erythrocyte called?
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reticulocyte
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What part of the body does erythropoietin (EPO) target to increase erythropoiesis?
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Bone Marrow
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What part of the hemoglobin molecule is recycled to form bile?
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a portion of the heme group
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What erythrocyte production disorder results from an autoimmune disease associated with vitamin B12 absorption?
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pernicious anemia
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What role do the kidneys play in erythropoiesis?
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The kidneys detect low levels of oxygen in the blood.
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Which of the following is NOT a part of hemostasis?
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vascular relaxation
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What protein involved in coagulation provides the scaffolding for tissue repair?
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Fibrin
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What is an embolus?
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a blood clot that has broken loose and is floating freely in the bloodstream
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Hemostasis leads to __________.
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Stoppage of bleeding
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The first step in hemostasis is __________.
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Vascular Spasm
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Which of the following represents a difference between extrinsic and intrinsic blood clotting pathways?
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One is faster than the other
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The enzyme __________ digests fibrin clots.
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Plasmin
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Which of the following would NOT lead to a bleeding disorder?
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Excess calcium in the Diet
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Which of the following is best suited to the clotting process that occurs when blood vessels are ruptured?
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Platelets
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Which event of hemostasis constricts the damaged artery to reduce blood loss? Select from letters A-D.
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A.
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During which event of hemostasis do clotting factors (procoagulants) assist with the transformation of blood from a liquid to a gel? Select from letters A-D.
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D.
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What "clot buster" enzyme removes unneeded clots after healing has occurred during fibrinolysis?
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Plasmin
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During erythroblastosis fetalis, a Rh- mother's anti-Rh antibodies that have crossed the placenta will cause agglutination of the fetus's Rh+ RBCs. However, the reverse problem never happens when a Rh+ mother is pregnant with a Rh- fetus, that is, antibodies produced by the fetus cannot cause agglutination of the mother's Rh+ RBCs. This is true because ______.
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antibodies that can cause this agglutination are not produced by a fetus
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Which ABO blood type is considered to be the universal donor?
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O
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A person who lacks agglutinogens A and B would have blood type __________.
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O
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Which of the following scenarios could result in HDN (hemolytic disease of the newborn)?
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B- female pregnant with an AB+ baby
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Choose the compatible transfusion.
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Donate type O blood to a recipient with type AB blood.
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A person's blood type is genetically determined.
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True
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What is hematocrit a measure of?
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Hematocrit is the percentage of erythrocytes in a whole blood sample.
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Which of the following does NOT serve as a site for blood cell production in the developing fetus?
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Intestines
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What is the average normal pH range of blood?
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7.35-7.45
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Which of the following is not a distribution function of blood?
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Transport of salts to maintain blood volume
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Which of the following is a protective function of blood?
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Prevention of Blood Loss
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Which of the following statements does not describe blood?
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Blood carriers body cells to injured areas for repair
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Which of the following is true about blood plasma?
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It is abut 90% water
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The plasma protein that is the major contributor to osmotic pressure is ________.
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Albumin
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The primary source of RBCs in the adult human being is the bone marrow in the shafts of the long bones.
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False
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Hemorrhagic anemias result from blood loss.
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True
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White blood cells are produced through the action of colony-stimulating factors.
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True
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Hemoglobin is made up of the protein heme and the red pigment globin.
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False
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Each hemoglobin molecule can transport two molecules of oxygen.
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False
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Diapedesis is the process by which red blood cells move into tissue spaces from the interior of blood capillaries.
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False
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Positive chemotaxis is a feedback system that signals leukocyte migration into damaged areas.
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True
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Basophils increase in number when parasitic invasion occurs.
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False
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Leukopenia is an abnormally low number of leukocytes.
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True
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Leukocytes move through the circulatory system by amoeboid motion.
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False
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Granulocytes called neutrophils are phagocytic and are the most numerous of all white blood cell types.
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True
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All lymphocytes are leukocytes, but not all leukocytes are lymphocytes.
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True
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Myelocytic leukemia involves a cancerous condition of lymphocytes.
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False
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Which of the following might trigger erythropoiesis?
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hypoxia of EPO-producing cells
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James has a hemoglobin measurement of 16 g/100 ml blood. This is ________.
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Within Normal Range
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All of the following can be expected with polycythemia except ________.
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low blood viscosity
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No visible cytoplasmic granules are present in ________.
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Monocytes
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Which of the following is characteristic of all leukocytes?
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They are nucleated
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Platelets ________.
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stick to the damaged area of a blood vessel and help seal the break
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Complications of aplastic anemia generally do not include ________.
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increase of leukocytes as a result of erythrocyte loss
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What organ in the body regulates erythrocyte production?
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Kidney
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Leukemia refers to cancerous conditions involving white blood cells.
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True
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The normal RBC "graveyard" is the liver.
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False
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Myeloid stem cells give rise to all leukocytes.
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False
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Which of the following is not a functional characteristic of WBCs?
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granulosis
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Which of the choices below is the parent cell for all formed elements of blood?
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hemocytoblast
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Blood reticulocyte counts provide information regarding ________.
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rate of erythrocyte formation
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Select the incorrect statement regarding blood cell formation.
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Platelets are formed from myeloblasts
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Which of the following is not a structural characteristic that contributes to erythrocyte gas transport functions?
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mitotically active
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A lack of intrinsic factor, leading to a deficiency of vitamin B12 and causing an appearance of large pale cells called macrocytes, is characteristic of ________.
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pernicious anemia
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Which of the following would not be a possible cause of sickling of red blood cells in someone with sickle-cell anemia?
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Sleeping in a well ventilated room
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The immediate response to blood vessel injury is clotting.
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False
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Which of the following is not a phase of hemostasis?
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fibrinolysis
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The slowest step in the clotting process is ________.
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formation of prothrombin activator
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Thromboembolic disorders ________.
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include embolus formation, a clot moving within the circulatory system
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Which of the following is not a cause of bleeding disorders?
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excess secretion of platelet-derived growth factor (PDGF)
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Which sequence is correct for the following events? 1. fibrinogen β†’ fibrin 2. clot retraction 3. formation of thromboplastin 4. prothrombin β†’ thrombin
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3, 4, 1, 2
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All of the following conditions impair coagulation except ________.
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vascular spasm
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The process of fibrinolysis disposes of bacteria when healing has occurred.
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False
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Clotting factor activation turns clotting factors into enzymes.
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True
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A person with type B blood could receive blood from a person with either type B or type O blood.
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True
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An individual who is blood type AB negative can ________.
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receive any blood type in moderate amounts except that with the Rh antigen
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Blood volume restorers include all of the following except ________.
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packed cells
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Fred's blood was determined to be AB positive. What does this mean?
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There are no antibodies to A, to B, or to Rh antigens in the plasma.
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When can erythroblastosis fetalis not possibly happen in the child of an Rh negative mother?
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f the father is Rh-
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Why would there be cause for concern if a young pregnant mother is Rh-, her husband is Rh+, and this is their second child?
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If the second child is Rh+ and the mother did not take RhoGAM, there is a chance that the child will develop erythroblastosis fetalis and die before birth
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Which blood type is generally called the universal donor?
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O
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Which of the statements below is an incorrect or false statement?
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Blood typing for the Kell, Lewis, and Duffy factors is always done before a blood transfusion.
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When neither anti-A serum nor anti-B serum cause clumping (agglutination) of donor cells on a slide, the blood type is ________.
answer
O
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A total WBC count and a differential WBC count have been ordered for Mrs. Johnson. What information is obtained from the differential count that the total count does not provide?
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The differential count determines the relative proportion of individual leukocyte types. The total WBC count indicates an increase or decrease in number of WBCs.
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A patient complains of no energy, a chronic sore throat, a low-grade fever, and is tired and achy. His doctor notes an enlarged spleen upon examination. What diagnosis would you expect, and what definitive test would you request?
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The diagnosis is infectious mononucleosis. The test would be a differential white blood cell count to look for elevated numbers of monocytes and atypical lymphocytes.
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The special type of hemoglobin present in fetal red blood cells is ________.
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hemoglobin F
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Fetal hemoglobin has a higher affinity for oxygen than does adult hemoglobin.
answer
True